Exploring Mannosylpurines as Copper Chelators and Cholinesterase Inhibitors with Potential for Alzheimer’s Disease

Alzheimer’s Disease (AD) is characterized by a progressive cholinergic neurotransmission imbalance, with a decrease of acetylcholinesterase (AChE) activity followed by a significant increase of butyrylcholinesterase (BChE) in the later AD stages. BChE activity is also crucial for the development of...

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Detalles Bibliográficos
Autores principales: Schino, Ignazio, Cantore, Mariangela, de Candia, Modesto, Altomare, Cosimo D., Maria, Catarina, Barros, João, Cachatra, Vasco, Calado, Patrícia, Shimizu, Karina, Freitas, Adilson A., Oliveira, Maria C., Ferreira, Maria J., Lopes, José N. C., Colabufo, Nicola A., Rauter, Amélia P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9864808/
https://www.ncbi.nlm.nih.gov/pubmed/36678552
http://dx.doi.org/10.3390/ph16010054

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