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Lab-on-a-Chip Technologies for Microgravity Simulation and Space Applications

Gravity plays an important role in the development of life on earth. The effect of gravity on living organisms can be investigated by controlling the magnitude of gravity. Most reduced gravity experiments are conducted on the Lower Earth Orbit (LEO) in the International Space Station (ISS). However,...

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Autores principales: Vashi, Aditya, Sreejith, Kamalalayam Rajan, Nguyen, Nam-Trung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9864955/
https://www.ncbi.nlm.nih.gov/pubmed/36677176
http://dx.doi.org/10.3390/mi14010116
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author Vashi, Aditya
Sreejith, Kamalalayam Rajan
Nguyen, Nam-Trung
author_facet Vashi, Aditya
Sreejith, Kamalalayam Rajan
Nguyen, Nam-Trung
author_sort Vashi, Aditya
collection PubMed
description Gravity plays an important role in the development of life on earth. The effect of gravity on living organisms can be investigated by controlling the magnitude of gravity. Most reduced gravity experiments are conducted on the Lower Earth Orbit (LEO) in the International Space Station (ISS). However, running experiments in ISS face challenges such as high cost, extreme condition, lack of direct accessibility, and long waiting period. Therefore, researchers have developed various ground-based devices and methods to perform reduced gravity experiments. However, the advantage of space conditions for developing new drugs, vaccines, and chemical applications requires more attention and new research. Advancements in conventional methods and the development of new methods are necessary to fulfil these demands. The advantages of Lab-on-a-Chip (LOC) devices make them an attractive option for simulating microgravity. This paper briefly reviews the advancement of LOC technologies for simulating microgravity in an earth-based laboratory.
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spelling pubmed-98649552023-01-22 Lab-on-a-Chip Technologies for Microgravity Simulation and Space Applications Vashi, Aditya Sreejith, Kamalalayam Rajan Nguyen, Nam-Trung Micromachines (Basel) Review Gravity plays an important role in the development of life on earth. The effect of gravity on living organisms can be investigated by controlling the magnitude of gravity. Most reduced gravity experiments are conducted on the Lower Earth Orbit (LEO) in the International Space Station (ISS). However, running experiments in ISS face challenges such as high cost, extreme condition, lack of direct accessibility, and long waiting period. Therefore, researchers have developed various ground-based devices and methods to perform reduced gravity experiments. However, the advantage of space conditions for developing new drugs, vaccines, and chemical applications requires more attention and new research. Advancements in conventional methods and the development of new methods are necessary to fulfil these demands. The advantages of Lab-on-a-Chip (LOC) devices make them an attractive option for simulating microgravity. This paper briefly reviews the advancement of LOC technologies for simulating microgravity in an earth-based laboratory. MDPI 2022-12-31 /pmc/articles/PMC9864955/ /pubmed/36677176 http://dx.doi.org/10.3390/mi14010116 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Vashi, Aditya
Sreejith, Kamalalayam Rajan
Nguyen, Nam-Trung
Lab-on-a-Chip Technologies for Microgravity Simulation and Space Applications
title Lab-on-a-Chip Technologies for Microgravity Simulation and Space Applications
title_full Lab-on-a-Chip Technologies for Microgravity Simulation and Space Applications
title_fullStr Lab-on-a-Chip Technologies for Microgravity Simulation and Space Applications
title_full_unstemmed Lab-on-a-Chip Technologies for Microgravity Simulation and Space Applications
title_short Lab-on-a-Chip Technologies for Microgravity Simulation and Space Applications
title_sort lab-on-a-chip technologies for microgravity simulation and space applications
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9864955/
https://www.ncbi.nlm.nih.gov/pubmed/36677176
http://dx.doi.org/10.3390/mi14010116
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