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Exploring the Molecular Pathogenesis, Pathogen Association, and Therapeutic Strategies against HPV Infection

The human papillomavirus (HPV), commonly documented as the cause of warts, has gained much interest recently due to its possible links to several types of cancer. HPV infection is discussed in this review from multiple angles, including its virology, epidemiology, etiology, immunology, clinical symp...

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Autores principales: Mukherjee, Anirban Goutam, Wanjari, Uddesh Ramesh, Gopalakrishnan, Abilash Valsala, Kannampuzha, Sandra, Murali, Reshma, Namachivayam, Arunraj, Ganesan, Raja, Renu, Kaviyarasi, Dey, Abhijit, Vellingiri, Balachandar, Prabakaran, D. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9865103/
https://www.ncbi.nlm.nih.gov/pubmed/36678374
http://dx.doi.org/10.3390/pathogens12010025
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author Mukherjee, Anirban Goutam
Wanjari, Uddesh Ramesh
Gopalakrishnan, Abilash Valsala
Kannampuzha, Sandra
Murali, Reshma
Namachivayam, Arunraj
Ganesan, Raja
Renu, Kaviyarasi
Dey, Abhijit
Vellingiri, Balachandar
Prabakaran, D. S.
author_facet Mukherjee, Anirban Goutam
Wanjari, Uddesh Ramesh
Gopalakrishnan, Abilash Valsala
Kannampuzha, Sandra
Murali, Reshma
Namachivayam, Arunraj
Ganesan, Raja
Renu, Kaviyarasi
Dey, Abhijit
Vellingiri, Balachandar
Prabakaran, D. S.
author_sort Mukherjee, Anirban Goutam
collection PubMed
description The human papillomavirus (HPV), commonly documented as the cause of warts, has gained much interest recently due to its possible links to several types of cancer. HPV infection is discussed in this review from multiple angles, including its virology, epidemiology, etiology, immunology, clinical symptoms, and treatment. Recent breakthroughs in molecular biology have led to the development of new methods for detecting and treating HPV in tissue. There is no cure for HPV, and although vaccines are available to prevent infection with the most common HPV viruses, their utilization is limited. Destruction and excision are the primary treatment modalities. This review sheds light on the epidemiology, molecular pathogenesis, the association of several other pathogens with HPV, the latest treatment strategies available to treat the same, and an overview of the progress made and the obstacles still to be overcome in the fight against HPV infection.
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spelling pubmed-98651032023-01-22 Exploring the Molecular Pathogenesis, Pathogen Association, and Therapeutic Strategies against HPV Infection Mukherjee, Anirban Goutam Wanjari, Uddesh Ramesh Gopalakrishnan, Abilash Valsala Kannampuzha, Sandra Murali, Reshma Namachivayam, Arunraj Ganesan, Raja Renu, Kaviyarasi Dey, Abhijit Vellingiri, Balachandar Prabakaran, D. S. Pathogens Review The human papillomavirus (HPV), commonly documented as the cause of warts, has gained much interest recently due to its possible links to several types of cancer. HPV infection is discussed in this review from multiple angles, including its virology, epidemiology, etiology, immunology, clinical symptoms, and treatment. Recent breakthroughs in molecular biology have led to the development of new methods for detecting and treating HPV in tissue. There is no cure for HPV, and although vaccines are available to prevent infection with the most common HPV viruses, their utilization is limited. Destruction and excision are the primary treatment modalities. This review sheds light on the epidemiology, molecular pathogenesis, the association of several other pathogens with HPV, the latest treatment strategies available to treat the same, and an overview of the progress made and the obstacles still to be overcome in the fight against HPV infection. MDPI 2022-12-23 /pmc/articles/PMC9865103/ /pubmed/36678374 http://dx.doi.org/10.3390/pathogens12010025 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Mukherjee, Anirban Goutam
Wanjari, Uddesh Ramesh
Gopalakrishnan, Abilash Valsala
Kannampuzha, Sandra
Murali, Reshma
Namachivayam, Arunraj
Ganesan, Raja
Renu, Kaviyarasi
Dey, Abhijit
Vellingiri, Balachandar
Prabakaran, D. S.
Exploring the Molecular Pathogenesis, Pathogen Association, and Therapeutic Strategies against HPV Infection
title Exploring the Molecular Pathogenesis, Pathogen Association, and Therapeutic Strategies against HPV Infection
title_full Exploring the Molecular Pathogenesis, Pathogen Association, and Therapeutic Strategies against HPV Infection
title_fullStr Exploring the Molecular Pathogenesis, Pathogen Association, and Therapeutic Strategies against HPV Infection
title_full_unstemmed Exploring the Molecular Pathogenesis, Pathogen Association, and Therapeutic Strategies against HPV Infection
title_short Exploring the Molecular Pathogenesis, Pathogen Association, and Therapeutic Strategies against HPV Infection
title_sort exploring the molecular pathogenesis, pathogen association, and therapeutic strategies against hpv infection
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9865103/
https://www.ncbi.nlm.nih.gov/pubmed/36678374
http://dx.doi.org/10.3390/pathogens12010025
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