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Exploring the Molecular Pathogenesis, Pathogen Association, and Therapeutic Strategies against HPV Infection
The human papillomavirus (HPV), commonly documented as the cause of warts, has gained much interest recently due to its possible links to several types of cancer. HPV infection is discussed in this review from multiple angles, including its virology, epidemiology, etiology, immunology, clinical symp...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9865103/ https://www.ncbi.nlm.nih.gov/pubmed/36678374 http://dx.doi.org/10.3390/pathogens12010025 |
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author | Mukherjee, Anirban Goutam Wanjari, Uddesh Ramesh Gopalakrishnan, Abilash Valsala Kannampuzha, Sandra Murali, Reshma Namachivayam, Arunraj Ganesan, Raja Renu, Kaviyarasi Dey, Abhijit Vellingiri, Balachandar Prabakaran, D. S. |
author_facet | Mukherjee, Anirban Goutam Wanjari, Uddesh Ramesh Gopalakrishnan, Abilash Valsala Kannampuzha, Sandra Murali, Reshma Namachivayam, Arunraj Ganesan, Raja Renu, Kaviyarasi Dey, Abhijit Vellingiri, Balachandar Prabakaran, D. S. |
author_sort | Mukherjee, Anirban Goutam |
collection | PubMed |
description | The human papillomavirus (HPV), commonly documented as the cause of warts, has gained much interest recently due to its possible links to several types of cancer. HPV infection is discussed in this review from multiple angles, including its virology, epidemiology, etiology, immunology, clinical symptoms, and treatment. Recent breakthroughs in molecular biology have led to the development of new methods for detecting and treating HPV in tissue. There is no cure for HPV, and although vaccines are available to prevent infection with the most common HPV viruses, their utilization is limited. Destruction and excision are the primary treatment modalities. This review sheds light on the epidemiology, molecular pathogenesis, the association of several other pathogens with HPV, the latest treatment strategies available to treat the same, and an overview of the progress made and the obstacles still to be overcome in the fight against HPV infection. |
format | Online Article Text |
id | pubmed-9865103 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-98651032023-01-22 Exploring the Molecular Pathogenesis, Pathogen Association, and Therapeutic Strategies against HPV Infection Mukherjee, Anirban Goutam Wanjari, Uddesh Ramesh Gopalakrishnan, Abilash Valsala Kannampuzha, Sandra Murali, Reshma Namachivayam, Arunraj Ganesan, Raja Renu, Kaviyarasi Dey, Abhijit Vellingiri, Balachandar Prabakaran, D. S. Pathogens Review The human papillomavirus (HPV), commonly documented as the cause of warts, has gained much interest recently due to its possible links to several types of cancer. HPV infection is discussed in this review from multiple angles, including its virology, epidemiology, etiology, immunology, clinical symptoms, and treatment. Recent breakthroughs in molecular biology have led to the development of new methods for detecting and treating HPV in tissue. There is no cure for HPV, and although vaccines are available to prevent infection with the most common HPV viruses, their utilization is limited. Destruction and excision are the primary treatment modalities. This review sheds light on the epidemiology, molecular pathogenesis, the association of several other pathogens with HPV, the latest treatment strategies available to treat the same, and an overview of the progress made and the obstacles still to be overcome in the fight against HPV infection. MDPI 2022-12-23 /pmc/articles/PMC9865103/ /pubmed/36678374 http://dx.doi.org/10.3390/pathogens12010025 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Mukherjee, Anirban Goutam Wanjari, Uddesh Ramesh Gopalakrishnan, Abilash Valsala Kannampuzha, Sandra Murali, Reshma Namachivayam, Arunraj Ganesan, Raja Renu, Kaviyarasi Dey, Abhijit Vellingiri, Balachandar Prabakaran, D. S. Exploring the Molecular Pathogenesis, Pathogen Association, and Therapeutic Strategies against HPV Infection |
title | Exploring the Molecular Pathogenesis, Pathogen Association, and Therapeutic Strategies against HPV Infection |
title_full | Exploring the Molecular Pathogenesis, Pathogen Association, and Therapeutic Strategies against HPV Infection |
title_fullStr | Exploring the Molecular Pathogenesis, Pathogen Association, and Therapeutic Strategies against HPV Infection |
title_full_unstemmed | Exploring the Molecular Pathogenesis, Pathogen Association, and Therapeutic Strategies against HPV Infection |
title_short | Exploring the Molecular Pathogenesis, Pathogen Association, and Therapeutic Strategies against HPV Infection |
title_sort | exploring the molecular pathogenesis, pathogen association, and therapeutic strategies against hpv infection |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9865103/ https://www.ncbi.nlm.nih.gov/pubmed/36678374 http://dx.doi.org/10.3390/pathogens12010025 |
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