Crystal Structure of the SH3 Domain of ASAP1 in Complex with the Proline Rich Motif (PRM) of MICAL1 Reveals a Unique SH3/PRM Interaction Mode

SH3 domains are common protein binding modules. The target sequence of SH3 domains is usually a proline-rich motif (PRM) containing a minimal “PxxP” sequence. The mechanism of how different SH3 domains specifically choose their targets from vast PxxP-containing sequences is still not very clear, as...

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Detalles Bibliográficos
Autores principales: Jia, Xuanyan, Lin, Leishu, Xu, Shun, Li, Lingxuan, Wei, Zhiyi, Yu, Cong, Niu, Fengfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9865144/
https://www.ncbi.nlm.nih.gov/pubmed/36674928
http://dx.doi.org/10.3390/ijms24021414

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9865144/
https://www.ncbi.nlm.nih.gov/pubmed/36674928
http://dx.doi.org/10.3390/ijms24021414

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