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Crystal Structure of the SH3 Domain of ASAP1 in Complex with the Proline Rich Motif (PRM) of MICAL1 Reveals a Unique SH3/PRM Interaction Mode
SH3 domains are common protein binding modules. The target sequence of SH3 domains is usually a proline-rich motif (PRM) containing a minimal “PxxP” sequence. The mechanism of how different SH3 domains specifically choose their targets from vast PxxP-containing sequences is still not very clear, as...
Autores principales: | Jia, Xuanyan, Lin, Leishu, Xu, Shun, Li, Lingxuan, Wei, Zhiyi, Yu, Cong, Niu, Fengfeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9865144/ https://www.ncbi.nlm.nih.gov/pubmed/36674928 http://dx.doi.org/10.3390/ijms24021414 |
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