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No Evidence of Ntwetwe Virus Infections in Children Presenting to Kiboga Hospital, Uganda
We investigated whether Ntwetwe virus—a novel orthobunyavirus discovered in a Ugandan girl with a fatal encephalopathy—was a common reason for hospital admission for children to Kiboga hospital, Uganda. A case–control was conducted between September 2019 and September 2020, including cases with seve...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9865167/ https://www.ncbi.nlm.nih.gov/pubmed/36668928 http://dx.doi.org/10.3390/tropicalmed8010021 |
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author | Edridge, Arthur W. D. van den Brekel, Nathalie Mukungu, Philly Nakayima, Rachael Bbosa, Samuel Isagara, Peter Boele van Hensbroek, Michael van der Hoek, Lia Kayiwa, John Lutwama, Julius J. Idro, Richard |
author_facet | Edridge, Arthur W. D. van den Brekel, Nathalie Mukungu, Philly Nakayima, Rachael Bbosa, Samuel Isagara, Peter Boele van Hensbroek, Michael van der Hoek, Lia Kayiwa, John Lutwama, Julius J. Idro, Richard |
author_sort | Edridge, Arthur W. D. |
collection | PubMed |
description | We investigated whether Ntwetwe virus—a novel orthobunyavirus discovered in a Ugandan girl with a fatal encephalopathy—was a common reason for hospital admission for children to Kiboga hospital, Uganda. A case–control was conducted between September 2019 and September 2020, including cases with severe neurological disease and mild febrile illness, matched to a healthy control without fever. Among 143 subjects, no cases with an acute infection were identified. This result suggests that Ntwetwe virus does not cause a major burden of disease amongst children presenting to Kiboga hospital during the study period. |
format | Online Article Text |
id | pubmed-9865167 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-98651672023-01-22 No Evidence of Ntwetwe Virus Infections in Children Presenting to Kiboga Hospital, Uganda Edridge, Arthur W. D. van den Brekel, Nathalie Mukungu, Philly Nakayima, Rachael Bbosa, Samuel Isagara, Peter Boele van Hensbroek, Michael van der Hoek, Lia Kayiwa, John Lutwama, Julius J. Idro, Richard Trop Med Infect Dis Communication We investigated whether Ntwetwe virus—a novel orthobunyavirus discovered in a Ugandan girl with a fatal encephalopathy—was a common reason for hospital admission for children to Kiboga hospital, Uganda. A case–control was conducted between September 2019 and September 2020, including cases with severe neurological disease and mild febrile illness, matched to a healthy control without fever. Among 143 subjects, no cases with an acute infection were identified. This result suggests that Ntwetwe virus does not cause a major burden of disease amongst children presenting to Kiboga hospital during the study period. MDPI 2022-12-27 /pmc/articles/PMC9865167/ /pubmed/36668928 http://dx.doi.org/10.3390/tropicalmed8010021 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Communication Edridge, Arthur W. D. van den Brekel, Nathalie Mukungu, Philly Nakayima, Rachael Bbosa, Samuel Isagara, Peter Boele van Hensbroek, Michael van der Hoek, Lia Kayiwa, John Lutwama, Julius J. Idro, Richard No Evidence of Ntwetwe Virus Infections in Children Presenting to Kiboga Hospital, Uganda |
title | No Evidence of Ntwetwe Virus Infections in Children Presenting to Kiboga Hospital, Uganda |
title_full | No Evidence of Ntwetwe Virus Infections in Children Presenting to Kiboga Hospital, Uganda |
title_fullStr | No Evidence of Ntwetwe Virus Infections in Children Presenting to Kiboga Hospital, Uganda |
title_full_unstemmed | No Evidence of Ntwetwe Virus Infections in Children Presenting to Kiboga Hospital, Uganda |
title_short | No Evidence of Ntwetwe Virus Infections in Children Presenting to Kiboga Hospital, Uganda |
title_sort | no evidence of ntwetwe virus infections in children presenting to kiboga hospital, uganda |
topic | Communication |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9865167/ https://www.ncbi.nlm.nih.gov/pubmed/36668928 http://dx.doi.org/10.3390/tropicalmed8010021 |
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