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A Comparative Study between A Protein Based Amorphous Formulation and Other Dissolution Rate Enhancing Approaches: A Case Study with Rifaximin

Amorphous solid dispersions (ASDs) based on proteins as co-formers have previously shown promising potential to improve the solubility and bioavailability of poorly water-soluble drugs. In particular, whey proteins have shown to be promising co-formers and amorphous stabilizers in ASD formulations,...

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Detalles Bibliográficos
Autores principales: Zhuo, Xuezhi, Margrethe Brekstad Kjellin, Maud, Schaal, Zarah, Zhang, Tengyu, Löbmann, Korbinian, Leng, Donglei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9865404/
https://www.ncbi.nlm.nih.gov/pubmed/36678757
http://dx.doi.org/10.3390/pharmaceutics15010126

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