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Structure-Based Identification of Natural-Product-Derived Compounds with Potential to Inhibit HIV-1 Entry

Broadly neutralizing antibodies (bNAbs) are potent in neutralizing a wide range of HIV strains. VRC01 is a CD4-binding-site (CD4-bs) class of bNAbs that binds to the conserved CD4-binding region of HIV-1 envelope (env) protein. Natural products that mimic VRC01 bNAbs by interacting with the conserve...

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Detalles Bibliográficos
Autores principales:	Ugwu-Korie, Nneka, Quaye, Osbourne, Wright, Edward, Languon, Sylvester, Agyapong, Odame, Broni, Emmanuel, Gupta, Yash, Kempaiah, Prakasha, Kwofie, Samuel K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9865492/ https://www.ncbi.nlm.nih.gov/pubmed/36677538 http://dx.doi.org/10.3390/molecules28020474

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