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The Association of Adherence to the Mediterranean Diet with Depression in Older Adults Longitudinally Taking into Account Cognitive Status: Results from the HELIAD Study
Although research has generally shown a negative association between depression and adherence to the Mediterranean diet (MeDi), the literature related to older adults is controversial, perhaps partially due to the fact that cognitive status has not been considered. The aim of the current work was to...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9865507/ https://www.ncbi.nlm.nih.gov/pubmed/36678230 http://dx.doi.org/10.3390/nu15020359 |
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author | Mamalaki, Eirini Ntanasi, Eva Hatzimanolis, Alexandros Basta, Maria Kosmidis, Mary H. Dardiotis, Efthimios Hadjigeorgiou, Giorgos M. Sakka, Paraskevi Scarmeas, Nikolaos Yannakoulia, Mary |
author_facet | Mamalaki, Eirini Ntanasi, Eva Hatzimanolis, Alexandros Basta, Maria Kosmidis, Mary H. Dardiotis, Efthimios Hadjigeorgiou, Giorgos M. Sakka, Paraskevi Scarmeas, Nikolaos Yannakoulia, Mary |
author_sort | Mamalaki, Eirini |
collection | PubMed |
description | Although research has generally shown a negative association between depression and adherence to the Mediterranean diet (MeDi), the literature related to older adults is controversial, perhaps partially due to the fact that cognitive status has not been considered. The aim of the current work was to investigate the association between MeDi and incident depression in a representative cohort of people, taking into account their cognitive status in multiple ways. The sample was drawn from the HELIAD study, a longitudinal study including a follow-up of 3 years after the baseline assessment. In total, 879 participants without depression at baseline were included (55.4% women, mean age ± Standard Deviation: 73.3 ± 5.0 years). Depression was determined as a score in the Geriatric depression scale ≥6 and/or antidepressant medication and/or clinical diagnosis of depression. Cox proportional hazard models adjusted for age, sex and education were employed. In the basic model, adherence to the MeDi was negatively associated with depression. In the most conservative model, excluding participants with dementia and Mild Cognitive Impairment, and after controlling for the baseline Cognitive Status, each unit (range 0–55) increase in MeDi was associated with a 6.2% decrease in the risk for depression (p < 0.001). These findings indicate that MeDi is negatively associated with depression longitudinally in older adults, above and beyond cognitive status. |
format | Online Article Text |
id | pubmed-9865507 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-98655072023-01-22 The Association of Adherence to the Mediterranean Diet with Depression in Older Adults Longitudinally Taking into Account Cognitive Status: Results from the HELIAD Study Mamalaki, Eirini Ntanasi, Eva Hatzimanolis, Alexandros Basta, Maria Kosmidis, Mary H. Dardiotis, Efthimios Hadjigeorgiou, Giorgos M. Sakka, Paraskevi Scarmeas, Nikolaos Yannakoulia, Mary Nutrients Article Although research has generally shown a negative association between depression and adherence to the Mediterranean diet (MeDi), the literature related to older adults is controversial, perhaps partially due to the fact that cognitive status has not been considered. The aim of the current work was to investigate the association between MeDi and incident depression in a representative cohort of people, taking into account their cognitive status in multiple ways. The sample was drawn from the HELIAD study, a longitudinal study including a follow-up of 3 years after the baseline assessment. In total, 879 participants without depression at baseline were included (55.4% women, mean age ± Standard Deviation: 73.3 ± 5.0 years). Depression was determined as a score in the Geriatric depression scale ≥6 and/or antidepressant medication and/or clinical diagnosis of depression. Cox proportional hazard models adjusted for age, sex and education were employed. In the basic model, adherence to the MeDi was negatively associated with depression. In the most conservative model, excluding participants with dementia and Mild Cognitive Impairment, and after controlling for the baseline Cognitive Status, each unit (range 0–55) increase in MeDi was associated with a 6.2% decrease in the risk for depression (p < 0.001). These findings indicate that MeDi is negatively associated with depression longitudinally in older adults, above and beyond cognitive status. MDPI 2023-01-11 /pmc/articles/PMC9865507/ /pubmed/36678230 http://dx.doi.org/10.3390/nu15020359 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Mamalaki, Eirini Ntanasi, Eva Hatzimanolis, Alexandros Basta, Maria Kosmidis, Mary H. Dardiotis, Efthimios Hadjigeorgiou, Giorgos M. Sakka, Paraskevi Scarmeas, Nikolaos Yannakoulia, Mary The Association of Adherence to the Mediterranean Diet with Depression in Older Adults Longitudinally Taking into Account Cognitive Status: Results from the HELIAD Study |
title | The Association of Adherence to the Mediterranean Diet with Depression in Older Adults Longitudinally Taking into Account Cognitive Status: Results from the HELIAD Study |
title_full | The Association of Adherence to the Mediterranean Diet with Depression in Older Adults Longitudinally Taking into Account Cognitive Status: Results from the HELIAD Study |
title_fullStr | The Association of Adherence to the Mediterranean Diet with Depression in Older Adults Longitudinally Taking into Account Cognitive Status: Results from the HELIAD Study |
title_full_unstemmed | The Association of Adherence to the Mediterranean Diet with Depression in Older Adults Longitudinally Taking into Account Cognitive Status: Results from the HELIAD Study |
title_short | The Association of Adherence to the Mediterranean Diet with Depression in Older Adults Longitudinally Taking into Account Cognitive Status: Results from the HELIAD Study |
title_sort | association of adherence to the mediterranean diet with depression in older adults longitudinally taking into account cognitive status: results from the heliad study |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9865507/ https://www.ncbi.nlm.nih.gov/pubmed/36678230 http://dx.doi.org/10.3390/nu15020359 |
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