Cargando…

β3 Adrenergic Receptor Agonist Mirabegron Increases AQP2 and NKCC2 Urinary Excretion in OAB Patients: A Pleiotropic Effect of Interest for Patients with X-Linked Nephrogenic Diabetes Insipidus

We previously reported the novel finding that β3-AR is functionally expressed in the renal tubule and shares its cellular localization with the vasopressin receptor AVPR2, whose physiological stimulation triggers antidiuresis by increasing the plasma membrane expression of the water channel AQP2 and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Milano, Serena, Maqoud, Fatima, Rutigliano, Monica, Saponara, Ilenia, Carmosino, Monica, Gerbino, Andrea, Lucarelli, Giuseppe, Battaglia, Michele, Svelto, Maria, Procino, Giuseppe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9865646/ https://www.ncbi.nlm.nih.gov/pubmed/36674662 http://dx.doi.org/10.3390/ijms24021136

Ejemplares similares

Hereditary Nephrogenic Diabetes Insipidus: Pathophysiology and Possible Treatment. An Update
por: Milano, Serena, et al.
Publicado: (2017)

Spilanthol from Acmella Oleracea Lowers the Intracellular Levels of cAMP Impairing NKCC2 Phosphorylation and Water Channel AQP2 Membrane Expression in Mouse Kidney
por: Gerbino, Andrea, et al.
Publicado: (2016)

Combination of secretin and fluvastatin ameliorates the polyuria associated with X-linked nephrogenic diabetes insipidus in mice
por: Procino, Giuseppe, et al.
Publicado: (2014)

TRPML1-Induced Lysosomal Ca(2+) Signals Activate AQP2 Translocation and Water Flux in Renal Collecting Duct Cells
por: Scorza, Simona Ida, et al.
Publicado: (2023)

High-throughput fluorescent-based NKCC functional assay in adherent epithelial cells
por: Carmosino, Monica, et al.
Publicado: (2013)

Activation of the Thiazide-Sensitive Sodium-Chloride Cotransporter by Beta3-Adrenoreceptor in the Distal Convoluted Tubule
por: Milano, Serena, et al.
Publicado: (2021)

A novel therapeutic effect of statins on nephrogenic diabetes insipidus
por: Bonfrate, Leonilde, et al.
Publicado: (2015)

AQP1-Containing Exosomes in Peritoneal Dialysis Effluent As Biomarker of Dialysis Efficiency
por: Corciulo, Simone, et al.
Publicado: (2019)

Role of Lamin A/C Gene Mutations in the Signaling Defects Leading to Cardiomyopathies
por: Gerbino, Andrea, et al.
Publicado: (2018)

MAL/VIP17, a New Player in the Regulation of NKCC2 in the Kidney
por: Carmosino, Monica, et al.
Publicado: (2010)

Aquaporin-1 Facilitates Transmesothelial Water Permeability: In Vitro and Ex Vivo Evidence and Possible Implications in Peritoneal Dialysis
por: Piccapane, Francesca, et al.
Publicado: (2021)

Histamine treatment induces rearrangements of orthogonal arrays of particles (OAPs) in human AQP4-expressing gastric cells
por: Carmosino, Monica, et al.
Publicado: (2001)

Dandelion Root Extract Induces Intracellular Ca(2+) Increases in HEK293 Cells
por: Gerbino, Andrea, et al.
Publicado: (2018)

β(3) adrenergic receptor in the kidney may be a new player in sympathetic regulation of renal function
por: Procino, Giuseppe, et al.
Publicado: (2016)

Functional study of a KCNH2 mutant: Novel insights on the pathogenesis of the LQT2 syndrome
por: De Zio, Roberta, et al.
Publicado: (2019)

Publisher Correction: Role of PKC in the Regulation of the Human Kidney Chloride Channel ClC-Ka
por: Gerbino, Andrea, et al.
Publicado: (2020)

Role of PKC in the Regulation of the Human Kidney Chloride Channel ClC-Ka
por: Gerbino, Andrea, et al.
Publicado: (2020)

A Novel Formulation of Glucose-Sparing Peritoneal Dialysis Solutions with l-Carnitine Improves Biocompatibility on Human Mesothelial Cells
por: Piccapane, Francesca, et al.
Publicado: (2020)

Further evidence for functional recovery of AQP2 mutations associated with nephrogenic diabetes insipidus
por: Bissonnette, Pierre, et al.
Publicado: (2021)

The expression of Lamin A mutant R321X leads to endoplasmic reticulum stress with aberrant Ca(2+) handling
por: Carmosino, Monica, et al.
Publicado: (2016)

Role of Nuclear Lamin A/C in the Regulation of Nav1.5 Channel and Microtubules: Lesson From the Pathogenic Lamin A/C Variant Q517X
por: De Zio, Roberta, et al.
Publicado: (2022)

Pro‐inflammatory cytokines as emerging molecular determinants in cardiolaminopathies
por: Gerbino, Andrea, et al.
Publicado: (2021)

Activation of AQP2 water channels without vasopressin: therapeutic strategies for congenital nephrogenic diabetes insipidus
por: Ando, Fumiaki, et al.
Publicado: (2018)

Novel AQP2 Mutations and Clinical Characteristics in Seven Chinese Families With Congenital Nephrogenic Diabetes Insipidus
por: Li, Qian, et al.
Publicado: (2021)

AKAPs-PKA disruptors increase AQP2 activity independently of vasopressin in a model of nephrogenic diabetes insipidus
por: Ando, Fumiaki, et al.
Publicado: (2018)

Activation of AQP2 water channels by protein kinase A: therapeutic strategies for congenital nephrogenic diabetes insipidus
por: Ando, Fumiaki
Publicado: (2021)

AQP2: Mutations Associated with Congenital Nephrogenic Diabetes Insipidus and Regulation by Post-Translational Modifications and Protein-Protein Interactions
por: Gao, Chao, et al.
Publicado: (2020)

Targeting unfolded protein response reverts ER stress and ER Ca(2+) homeostasis in cardiomyocytes expressing the pathogenic variant of Lamin A/C R321X
por: Pietrafesa, Giusy, et al.
Publicado: (2023)

Partial nephrogenic diabetes insipidus caused by a novel AQP2 variation impairing trafficking of the aquaporin-2 water channel
por: Dollerup, Pia, et al.
Publicado: (2015)

A Novel AQP2 Sequence Variant Causing Aquaporin-2 Retention in the Cytoplasm and Autosomal Dominant Nephrogenic Diabetes Insipidus
por: Hinrichs, Gitte R., et al.
Publicado: (2022)

The AQP2 mutation V71M causes nephrogenic diabetes insipidus in humans but does not impair the function of a bacterial homolog
por: Klein, Noreen, et al.
Publicado: (2015)

Acquired nephrogenic diabetes insipidus in a dog with leptospirosis
por: Etish, Jamie L, et al.
Publicado: (2014)

Partial nephrogenic diabetes insipidus associated with Castleman’s disease
por: Kim, Minah, et al.
Publicado: (2019)

Progranulin Deficient Mice Develop Nephrogenic Diabetes Insipidus
por: Hardt, Stefanie, et al.
Publicado: (2018)

Long-term outcome in inherited nephrogenic diabetes insipidus
por: Sharma, Sonia, et al.
Publicado: (2018)

Sevoflurane and nephrogenic diabetes insipidus on the rise: copeptin to the rescue?
por: Honore, Patrick M., et al.
Publicado: (2019)

Long-term outcome in inherited nephrogenic diabetes insipidus
por: Sharma, Sonia, et al.
Publicado: (2020)

Sevoflurane: Nephrogenic diabetes insipidus: 2 case reports
Publicado: (2021)

Severe congenital nephrogenic diabetes insipidus in a compound heterozygote with a new large deletion of the AQP2 gene. A case report
por: Peces, Ramón, et al.
Publicado: (2019)

Real-world persistence and adherence to oral antimuscarinics and mirabegron in patients with overactive bladder (OAB): a systematic literature review
por: Yeowell, Gillian, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_updlk9g8m1fbatfsu520nqtpbb