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Structural Insights of the DciA Helicase Loader in Its Relationship with DNA

DciA is the ancestral bacterial replicative helicase loader, punctually replaced during evolution by the DnaC/I loaders of phage origin. DnaC helps the helicase to load onto DNA by cracking open the hexameric ring, but the mechanism of loading by DciA remains unknown. We demonstrate by electron micr...

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Detalles Bibliográficos
Autores principales: Cargemel, Claire, Baconnais, Sonia, Aumont-Nicaise, Magali, Noiray, Magali, Maurin, Lia, Andreani, Jessica, Walbott, Hélène, Le Cam, Eric, Ochsenbein, Françoise, Marsin, Stéphanie, Quevillon-Cheruel, Sophie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9865707/
https://www.ncbi.nlm.nih.gov/pubmed/36674944
http://dx.doi.org/10.3390/ijms24021427