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Diosmin Mitigates Gentamicin-Induced Nephrotoxicity in Rats: Insights on miR-21 and -155 Expression, Nrf2/HO-1 and p38-MAPK/NF-κB Pathways

Gentamicin (GNT) is the most frequently used aminoglycoside. However, its therapeutic efficacy is limited due to nephrotoxicity. Thus, the potential anticipatory effect of Diosmin (DIOS) against GNT-prompted kidney damage in rats together with the putative nephroprotective pathways were scrutinized....

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Detalles Bibliográficos
Autores principales:	Nadeem, Rania I., Aboutaleb, Amany S., Younis, Nancy S., Ahmed, Hebatalla I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9865818/ https://www.ncbi.nlm.nih.gov/pubmed/36668774 http://dx.doi.org/10.3390/toxics11010048

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