Genetic Approaches for the Treatment of Giant Axonal Neuropathy

Giant axonal neuropathy (GAN) is a pediatric, hereditary, neurodegenerative disorder that affects both the central and peripheral nervous systems. It is caused by mutations in the GAN gene, which codes for the gigaxonin protein. Gigaxonin plays a role in intermediate filament (IF) turnover hence los...

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Detalles Bibliográficos
Autores principales: Shirakaki, Satomi, Roshmi, Rohini Roy, Yokota, Toshifumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9865904/
https://www.ncbi.nlm.nih.gov/pubmed/36675752
http://dx.doi.org/10.3390/jpm13010091

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9865904/
https://www.ncbi.nlm.nih.gov/pubmed/36675752
http://dx.doi.org/10.3390/jpm13010091

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