Cytoplasmic Expression of TP53INP2 Modulated by Demethylase FTO and Mutant NPM1 Promotes Autophagy in Leukemia Cells

Acute myeloid leukemia (AML) with a nucleophosmin 1 (NPM1) mutation is a unique subtype of adult leukemia. Recent studies show that NPM1-mutated AML has high autophagy activity. However, the mechanism for upholding the high autophagic level is still not fully elucidated. In this study, we first iden...

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Detalles Bibliográficos
Autores principales: Huang, Junpeng, Sun, Minghui, Tao, Yonghong, Ren, Jun, Peng, Meixi, Jing, Yipei, Xiao, Qiaoling, Yang, Jing, Lin, Can, Lei, Li, Yang, Zailin, Zhang, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9865930/
https://www.ncbi.nlm.nih.gov/pubmed/36675134
http://dx.doi.org/10.3390/ijms24021624

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9865930/
https://www.ncbi.nlm.nih.gov/pubmed/36675134
http://dx.doi.org/10.3390/ijms24021624

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