Cargando…

Identification of Nanoparticle Properties for Optimal Drug Delivery across a Physiological Cell Barrier

Nanoparticles (NPs) represent an attractive strategy to overcome difficulties associated with the delivery of therapeutics. Knowing the optimal properties of NPs to address these issues could allow for improved in vivo responses. This work investigated NPs prepared from 5 materials of 3 sizes and 3...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ross, Aisling M., Cahalane, Rachel M., Walsh, Darragh R., Grabrucker, Andreas M., Marcar, Lynnette, Mulvihill, John J. E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9865979/ https://www.ncbi.nlm.nih.gov/pubmed/36678829 http://dx.doi.org/10.3390/pharmaceutics15010200

Ejemplares similares

The effect of serum starvation on tight junctional proteins and barrier formation in Caco-2 cells
por: Ross, Aisling M., et al.
Publicado: (2021)

Drug delivery across physiological barriers /
Publicado: (2016)

A blood biomarker and clinical correlation cohort study protocol to diagnose sports-related concussion and monitor recovery in elite rugby
por: Kearns, Jamie, et al.
Publicado: (2020)

Overcoming Physiological Barriers to Nanoparticle Delivery—Are We There Yet?
por: Thomas, Oliver S., et al.
Publicado: (2019)

Ultrasound-targeted nanoparticle delivery across the blood-brain barrier
por: Price, Richard
Publicado: (2015)

Ultrasound-mediated delivery of brain-penetrating nanoparticles across the blood-tumor barrier
por: Timbie, Kelsie, et al.
Publicado: (2015)

The Role of Dietary Lipids in Cognitive Health: Implications for Neurodegenerative Disease
por: Hans, Sakshi, et al.
Publicado: (2022)

Effective transvascular delivery of nanoparticles across the blood-brain tumor barrier into malignant glioma cells
por: Sarin, Hemant, et al.
Publicado: (2008)

Iron uptake and transport across physiological barriers
por: Duck, Kari A., et al.
Publicado: (2016)

Autoregulated paracellular clearance of amyloid-β across the blood-brain barrier
por: Keaney, James, et al.
Publicado: (2015)

Zinc Binding to S100B Affords Regulation of Trace Metal Homeostasis and Excitotoxicity in the Brain
por: Hagmeyer, Simone, et al.
Publicado: (2018)

Systemic physiology augmented functional near-infrared spectroscopy hyperscanning: a first evaluation investigating entrainment of spontaneous activity of brain and body physiology between subjects
por: Guglielmini, Sabino, et al.
Publicado: (2022)

Nanoparticle Strategies to Improve the Delivery of Anticancer Drugs across the Blood–Brain Barrier to Treat Brain Tumors
por: Vanbilloen, Wouter J. F., et al.
Publicado: (2023)

Systematic, balancing gradients in neuron density and number across the primate isocortex
por: Cahalane, Diarmuid J., et al.
Publicado: (2012)

Self-assembled α-Tocopherol Transfer Protein Nanoparticles Promote Vitamin E Delivery Across an Endothelial Barrier
por: Aeschimann, Walter, et al.
Publicado: (2017)

Gender Dependent Evaluation of Autism like Behavior in Mice Exposed to Prenatal Zinc Deficiency
por: Grabrucker, Stefanie, et al.
Publicado: (2016)

Nanoparticle Mediated P-Glycoprotein Silencing for Improved Drug Delivery across the Blood-Brain Barrier: A siRNA-Chitosan Approach
por: Malmo, Jostein, et al.
Publicado: (2013)

ROS responsive resveratrol delivery from LDLR peptide conjugated PLA-coated mesoporous silica nanoparticles across the blood–brain barrier
por: Shen, Yang, et al.
Publicado: (2018)

Delivery across the blood-brain barrier: nanomedicine for glioblastoma multiforme
por: Jena, Lynn, et al.
Publicado: (2019)

Transporter-Guided Delivery of Nanoparticles to Improve Drug Permeation across Cellular Barriers and Drug Exposure to Selective Cell Types
por: Kou, Longfa, et al.
Publicado: (2018)

Physiological Benefits of Novel Selenium Delivery via Nanoparticles
por: Au, Alice, et al.
Publicado: (2023)

Environmental Factors in Autism
por: Grabrucker, Andreas M.
Publicado: (2013)

A Role for Synaptic Zinc in ProSAP/Shank PSD Scaffold Malformation in Autism Spectrum Disorders
por: Grabrucker, Andreas M
Publicado: (2014)

Non-Genetic Modifiers of Synaptic Plasticity and Neurotransmission in the Central Nervous System (CNS) in Health and Disease
por: Grabrucker, Andreas M.
Publicado: (2022)

Object Phobia and Altered RhoA Signaling in Amygdala of Mice Lacking RICH2
por: Sarowar, Tasnuva, et al.
Publicado: (2017)

Delivery of Nanoparticles across the Intestinal Epithelium via the Transferrin Transport Pathway
por: Yong, Jing M., et al.
Publicado: (2019)

How our hearts beat together: a study on physiological synchronization based on a self-paced joint motor task
por: Flory, Stephan, et al.
Publicado: (2023)

Mechanical and structural characterisation of the dural venous sinuses
por: Walsh, Darragh R., et al.
Publicado: (2020)

Nanoparticles for vaccine and gene therapy: Overcoming the barriers to nucleic acid delivery
por: Mollé, Lara M., et al.
Publicado: (2022)

Transcellular Model for Neutral and Charged Nanoparticles Across an In Vitro Blood–Brain Barrier
por: Zhang, Lin, et al.
Publicado: (2020)

Magnetic nanoformulation of azidothymidine 5’-triphosphate for targeted delivery across the blood–brain barrier
por: Saiyed, Zainulabedin M, et al.
Publicado: (2010)

Current approaches to enhance CNS delivery of drugs across the brain barriers
por: Lu, Cui-Tao, et al.
Publicado: (2014)

Nanomaterials Designed for Antiviral Drug Delivery Transport across Biological Barriers
por: Cojocaru, Florina-Daniela, et al.
Publicado: (2020)

Current Strategies to Enhance Delivery of Drugs across the Blood–Brain Barrier
por: Teleanu, Raluca Ioana, et al.
Publicado: (2022)

Established and Emerging Strategies for Drug Delivery Across the Blood-Brain Barrier in Brain Cancer
por: Parodi, Alessandro, et al.
Publicado: (2019)

Physiological and Pathological Factors Affecting Drug Delivery to the Brain by Nanoparticles
por: Islam, Yamir, et al.
Publicado: (2021)

Crossing the Blood-Brain Barrier: Advances in Nanoparticle Technology for Drug Delivery in Neuro-Oncology
por: Hersh, Andrew M., et al.
Publicado: (2022)

Nanomedicine against Aβ Aggregation by β–Sheet Breaker Peptide Delivery: In Vitro Evidence
por: Pederzoli, Francesca, et al.
Publicado: (2019)

Tissue inhibitor of matrix metalloproteinases-1 loaded poly(lactic-co-glycolic acid) nanoparticles for delivery across the blood–brain barrier
por: Chaturvedi, Mayank, et al.
Publicado: (2014)

Polymeric Nanoparticles Properties and Brain Delivery
por: Ribovski, Laís, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_7ltl215okn6ub11r8j5etits7v