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BIreactive: Expanding the Scope of Reactivity Predictions to Propynamides

We present the first comprehensive study on the prediction of reactivity for propynamides. Covalent inhibitors like propynamides often show improved potency, selectivity, and unique pharmacologic properties compared to their non-covalent counterparts. In order to achieve this, it is essential to tun...

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Detalles Bibliográficos
Autores principales:	Hermann, Markus R., Tautermann, Christofer S., Sieger, Peter, Grundl, Marc A., Weber, Alexander
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9866037/ https://www.ncbi.nlm.nih.gov/pubmed/36678612 http://dx.doi.org/10.3390/ph16010116

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