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Residual Behavior and Dietary Risk Assessment of Chlorfenapyr and Its Metabolites in Radish

Chlorfenapyr, as a highly effective and low-toxicity insect growth regulation inhibitor, has been used to control cross-cruciferous vegetable pests. However, the pesticide residue caused by its application threatens human health. In this paper, the residue digestion and final residue of chlorfenapyr...

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Autores principales: Sun, Mingna, Yi, Xiaotong, Tong, Zhou, Dong, Xu, Chu, Yue, Meng, Dandan, Duan, Jinsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9866042/
https://www.ncbi.nlm.nih.gov/pubmed/36677638
http://dx.doi.org/10.3390/molecules28020580
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author Sun, Mingna
Yi, Xiaotong
Tong, Zhou
Dong, Xu
Chu, Yue
Meng, Dandan
Duan, Jinsheng
author_facet Sun, Mingna
Yi, Xiaotong
Tong, Zhou
Dong, Xu
Chu, Yue
Meng, Dandan
Duan, Jinsheng
author_sort Sun, Mingna
collection PubMed
description Chlorfenapyr, as a highly effective and low-toxicity insect growth regulation inhibitor, has been used to control cross-cruciferous vegetable pests. However, the pesticide residue caused by its application threatens human health. In this paper, the residue digestion and final residue of chlorfenapyr in radish were studied in a field experiment. The results of the dynamic digestion test showed that the half-life of chlorfenapyr in radish leaves ranged from 6.0 to 6.4 days, and the digestion rate was fast. The median residual values of chlorfenapyr in radish and radish leaves at 14 days after treatment were 0.12 and 3.92 mg/kg, respectively. The results of the dietary intake risk assessment showed that the national estimated daily intake (NEDI) of chlorfenapyr in various populations in China were 0.373 and 5.66 µg/(kg bw·d), respectively. The risk entropy (RQ) was 0.012 and 0.147, respectively, indicating that the chronic dietary intake risk of chlorfenapyr in radish was low. The results of this study provided data support and a theoretical basis for guiding the scientific use of chlorfenapyr in radish production and evaluating the dietary risk of chlorfenapyr in vegetables.
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spelling pubmed-98660422023-01-22 Residual Behavior and Dietary Risk Assessment of Chlorfenapyr and Its Metabolites in Radish Sun, Mingna Yi, Xiaotong Tong, Zhou Dong, Xu Chu, Yue Meng, Dandan Duan, Jinsheng Molecules Article Chlorfenapyr, as a highly effective and low-toxicity insect growth regulation inhibitor, has been used to control cross-cruciferous vegetable pests. However, the pesticide residue caused by its application threatens human health. In this paper, the residue digestion and final residue of chlorfenapyr in radish were studied in a field experiment. The results of the dynamic digestion test showed that the half-life of chlorfenapyr in radish leaves ranged from 6.0 to 6.4 days, and the digestion rate was fast. The median residual values of chlorfenapyr in radish and radish leaves at 14 days after treatment were 0.12 and 3.92 mg/kg, respectively. The results of the dietary intake risk assessment showed that the national estimated daily intake (NEDI) of chlorfenapyr in various populations in China were 0.373 and 5.66 µg/(kg bw·d), respectively. The risk entropy (RQ) was 0.012 and 0.147, respectively, indicating that the chronic dietary intake risk of chlorfenapyr in radish was low. The results of this study provided data support and a theoretical basis for guiding the scientific use of chlorfenapyr in radish production and evaluating the dietary risk of chlorfenapyr in vegetables. MDPI 2023-01-06 /pmc/articles/PMC9866042/ /pubmed/36677638 http://dx.doi.org/10.3390/molecules28020580 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Sun, Mingna
Yi, Xiaotong
Tong, Zhou
Dong, Xu
Chu, Yue
Meng, Dandan
Duan, Jinsheng
Residual Behavior and Dietary Risk Assessment of Chlorfenapyr and Its Metabolites in Radish
title Residual Behavior and Dietary Risk Assessment of Chlorfenapyr and Its Metabolites in Radish
title_full Residual Behavior and Dietary Risk Assessment of Chlorfenapyr and Its Metabolites in Radish
title_fullStr Residual Behavior and Dietary Risk Assessment of Chlorfenapyr and Its Metabolites in Radish
title_full_unstemmed Residual Behavior and Dietary Risk Assessment of Chlorfenapyr and Its Metabolites in Radish
title_short Residual Behavior and Dietary Risk Assessment of Chlorfenapyr and Its Metabolites in Radish
title_sort residual behavior and dietary risk assessment of chlorfenapyr and its metabolites in radish
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9866042/
https://www.ncbi.nlm.nih.gov/pubmed/36677638
http://dx.doi.org/10.3390/molecules28020580
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