Electroreductively Induced Radicals for Organic Synthesis

Organic electrochemistry has attracted tremendous interest within the novel sustainable methodologies that have not only reduced the undesired byproducts, but also utilized cleaner and renewable energy sources. Particularly, oxidative electrochemistry has gained major attention. On the contrary, red...

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Detalles Bibliográficos
Autores principales: Xiang, Huaming, He, Jinyu, Qian, Weifeng, Qiu, Mingqiang, Xu, Hao, Duan, Wenxi, Ouyang, Yanyan, Wang, Yanzhao, Zhu, Cuiju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9866059/
https://www.ncbi.nlm.nih.gov/pubmed/36677915
http://dx.doi.org/10.3390/molecules28020857
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author Xiang, Huaming
He, Jinyu
Qian, Weifeng
Qiu, Mingqiang
Xu, Hao
Duan, Wenxi
Ouyang, Yanyan
Wang, Yanzhao
Zhu, Cuiju
author_facet Xiang, Huaming
He, Jinyu
Qian, Weifeng
Qiu, Mingqiang
Xu, Hao
Duan, Wenxi
Ouyang, Yanyan
Wang, Yanzhao
Zhu, Cuiju
author_sort Xiang, Huaming
collection PubMed
description Organic electrochemistry has attracted tremendous interest within the novel sustainable methodologies that have not only reduced the undesired byproducts, but also utilized cleaner and renewable energy sources. Particularly, oxidative electrochemistry has gained major attention. On the contrary, reductive electrolysis remains an underexplored research direction. In this context, we discuss advances in transition-metal-free cathodically generated radicals for selective organic transformations since 2016. We highlight the electroreductive reaction of alkyl radicals, aryl radicals, acyl radicals, silyl radicals, fluorosulfonyl radicals and trifluoromethoxyl radicals.
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spelling pubmed-98660592023-01-22 Electroreductively Induced Radicals for Organic Synthesis Xiang, Huaming He, Jinyu Qian, Weifeng Qiu, Mingqiang Xu, Hao Duan, Wenxi Ouyang, Yanyan Wang, Yanzhao Zhu, Cuiju Molecules Review Organic electrochemistry has attracted tremendous interest within the novel sustainable methodologies that have not only reduced the undesired byproducts, but also utilized cleaner and renewable energy sources. Particularly, oxidative electrochemistry has gained major attention. On the contrary, reductive electrolysis remains an underexplored research direction. In this context, we discuss advances in transition-metal-free cathodically generated radicals for selective organic transformations since 2016. We highlight the electroreductive reaction of alkyl radicals, aryl radicals, acyl radicals, silyl radicals, fluorosulfonyl radicals and trifluoromethoxyl radicals. MDPI 2023-01-15 /pmc/articles/PMC9866059/ /pubmed/36677915 http://dx.doi.org/10.3390/molecules28020857 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Xiang, Huaming
He, Jinyu
Qian, Weifeng
Qiu, Mingqiang
Xu, Hao
Duan, Wenxi
Ouyang, Yanyan
Wang, Yanzhao
Zhu, Cuiju
Electroreductively Induced Radicals for Organic Synthesis
title Electroreductively Induced Radicals for Organic Synthesis
title_full Electroreductively Induced Radicals for Organic Synthesis
title_fullStr Electroreductively Induced Radicals for Organic Synthesis
title_full_unstemmed Electroreductively Induced Radicals for Organic Synthesis
title_short Electroreductively Induced Radicals for Organic Synthesis
title_sort electroreductively induced radicals for organic synthesis
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9866059/
https://www.ncbi.nlm.nih.gov/pubmed/36677915
http://dx.doi.org/10.3390/molecules28020857
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AT xuhao electroreductivelyinducedradicalsfororganicsynthesis
AT duanwenxi electroreductivelyinducedradicalsfororganicsynthesis
AT ouyangyanyan electroreductivelyinducedradicalsfororganicsynthesis
AT wangyanzhao electroreductivelyinducedradicalsfororganicsynthesis
AT zhucuiju electroreductivelyinducedradicalsfororganicsynthesis

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