Cargando…

Proteomic Assessment of Hypoxia-Pre-Conditioned Human Bone Marrow Mesenchymal Stem Cell-Derived Extracellular Vesicles Demonstrates Promise in the Treatment of Cardiovascular Disease

Human bone marrow mesenchymal stem cell derived-extracellular vesicles (HBMSC-EV) are known for their regenerative and anti-inflammatory effects in animal models of myocardial ischemia. However, it is not known whether the efficacy of the EVs can be modulated by pre-conditioning of HBMSC by exposing...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xu, Cynthia M., Karbasiafshar, Catherine, Brinck Teixeira, Rayane, Ahsan, Nagib, Blume Corssac, Giana, Sellke, Frank W., Abid, M. Ruhul
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9866304/ https://www.ncbi.nlm.nih.gov/pubmed/36675188 http://dx.doi.org/10.3390/ijms24021674

Ejemplares similares

Reduction in mitochondrial ROS improves oxidative phosphorylation and provides resilience to coronary endothelium in non-reperfused myocardial infarction
por: Teixeira, Rayane Brinck, et al.
Publicado: (2023)

Visualization of cardiac uptake of bone marrow mesenchymal stem cell‐derived extracellular vesicles after intramyocardial or intravenous injection in murine myocardial infarction
por: Xu, Cynthia M., et al.
Publicado: (2023)

Optimization of mito-roGFP protocol to measure mitochondrial oxidative status in human coronary artery endothelial cells
por: Teixeira, Rayane Brinck, et al.
Publicado: (2021)

Delivery of a mitochondria‐targeted antioxidant from biocompatible, polymeric nanofibrous scaffolds
por: Hamedani, Yasaman, et al.
Publicado: (2020)

The Relationship Between Reactive Oxygen Species and Endothelial Cell Metabolism
por: Alhayaza, Raid, et al.
Publicado: (2020)

Clinical Application of Novel Therapies for Coronary Angiogenesis: Overview, Challenges, and Prospects
por: Sabra, Mohamed, et al.
Publicado: (2021)

Intramyocardial injection of hypoxia-conditioned extracellular vesicles modulates apoptotic signaling in chronically ischemic myocardium
por: Harris, Dwight D., et al.
Publicado: (2023)

Extracellular Vesicles Promote Arteriogenesis in Chronically Ischemic Myocardium in the Setting of Metabolic Syndrome
por: Scrimgeour, Laura A., et al.
Publicado: (2019)

Comparative Analysis of Normoxia- and Hypoxia-Modified Extracellular Vesicle Therapy in Function, Perfusion, and Collateralization in Chronically Ischemic Myocardium
por: Sabe, Sharif A., et al.
Publicado: (2023)

Effects of High Fat Versus Normal Diet on Extracellular Vesicle–Induced Angiogenesis in a Swine Model of Chronic Myocardial Ischemia
por: Aboulgheit, Ahmed, et al.
Publicado: (2021)

Antioxidant Therapy: Is it your Gateway to Improved Cardiovascular Health?
por: Abid, M Ruhul, et al.
Publicado: (2014)

Extracellular Vesicle Injection Improves Myocardial Function and Increases Angiogenesis in a Swine Model of Chronic Ischemia
por: Potz, Brittany A., et al.
Publicado: (2018)

Intravenous injection of extracellular vesicles to treat chronic myocardial ischemia
por: Scrimgeour, Laura A., et al.
Publicado: (2020)

Circulating Total Extracellular Vesicles Cargo Are Associated with Age-Related Oxidative Stress and Susceptibility to Cardiovascular Diseases: Exploratory Results from Microarray Data
por: Cechinel, Laura Reck, et al.
Publicado: (2023)

Pequi Fruit Extract Increases Antioxidant Enzymes and Reduces Oxidants in Human Coronary Artery Endothelial Cells
por: Braga, Karla M. S., et al.
Publicado: (2022)

Subcellular Reactive Oxygen Species (ROS) in Cardiovascular Pathophysiology
por: Aldosari, Sarah, et al.
Publicado: (2018)

Sitagliptin therapy improves myocardial perfusion and arteriolar collateralization in chronically ischemic myocardium: A pilot study
por: Sabe, Sharif A., et al.
Publicado: (2023)

Efeitos do Óleo de Copaíba em Marcadores Periféricos de Estresse Oxidativo em um Modelo de Cor Pulmonale em Ratos
por: Campos, Cristina, et al.
Publicado: (2021)

CSF extracellular vesicle proteomics demonstrates altered protein homeostasis in amyotrophic lateral sclerosis
por: Thompson, Alexander G., et al.
Publicado: (2020)

Canagliflozin Improves Myocardial Perfusion, Fibrosis, and Function in a Swine Model of Chronic Myocardial Ischemia
por: Sabe, Sharif A., et al.
Publicado: (2022)

Proteomic Analysis of Hypoxia-Induced Senescence of Human Bone Marrow Mesenchymal Stem Cells
por: Mai, Liping, et al.
Publicado: (2021)

Vesicles that promise enlargement
por: LeBrasseur, Nicole
Publicado: (2002)

Hypoxia-Induced Adaptations of miRNomes and Proteomes in Melanoma Cells and Their Secreted Extracellular Vesicles
por: Walbrecq, Geoffroy, et al.
Publicado: (2020)

Avelumab demonstrates promise in advanced NSCLC
por: Marciscano, Ariel E., et al.
Publicado: (2017)

Impact of exosomal HIV-1 Tat expression on the human cellular proteome
por: Lu, Huafei, et al.
Publicado: (2019)

An early stage in T4-induced hyperthyroidism is related to systemic oxidative stress but does not influence the pentose cycle in erythrocytes and systemic inflammatory status
por: Teixeira, Rayane Brinck, et al.
Publicado: (2019)

Endothelial Extracellular Vesicles—Promises and Challenges
por: Hromada, Carina, et al.
Publicado: (2017)

Demonstration of human mast cell progenitors in the bone marrow
por: Salomonsson, Maya, et al.
Publicado: (2019)

Therapeutic Use of Exercising in Hypoxia: Promises and Limitations
por: Millet, Gregoire P., et al.
Publicado: (2016)

Extracellular Vesicles Derived from Osteogenic-Differentiated Human Bone Marrow-Derived Mesenchymal Cells Rescue Osteogenic Ability of Bone Marrow-Derived Mesenchymal Cells Impaired by Hypoxia
por: Wang, Chenglong, et al.
Publicado: (2023)

Differential proteomic analysis and pathogenic effects of outer membrane vesicles derived from Acinetobacter baumannii under normoxia and hypoxia
por: Suzuki, Sachio, et al.
Publicado: (2023)

Extracellular Vesicles and the Promise of Continuous Liquid Biopsies
por: Armstrong, Don, et al.
Publicado: (2018)

Perils and Promises of Pathogenic Protozoan Extracellular Vesicles
por: Olajide, Joshua Seun, et al.
Publicado: (2020)

Skin sensitization by misonidazole: a demonstration of uniform mild hypoxia.
por: Stewart, F. A., et al.
Publicado: (1982)

Proteomics of Extracellular Vesicle in Glioblastoma
por: Lee, Yoon-Jin, et al.
Publicado: (2022)

The Promise of Proteomics for the Study of ADP-Ribosylation
por: Daniels, Casey M., et al.
Publicado: (2015)

Molecular responses to hypoxia: ancient pathways, clinical promises
por: Kim, William Y, et al.
Publicado: (2009)

Novel neutrophil extracellular trap-related mechanisms in diabetic wounds inspire a promising treatment strategy with hypoxia-challenged small extracellular vesicles
por: Chu, Ziqiang, et al.
Publicado: (2023)

Small Extracellular Vesicles from Head and Neck Squamous Cell Carcinoma Cells Carry a Proteomic Signature for Tumor Hypoxia
por: Głuszko, Alicja, et al.
Publicado: (2021)

Toosendanin demonstrates promising antitumor efficacy in osteosarcoma by targeting STAT3
por: Zhang, T, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_qfcd3otrdkuqrcdcpugco7amku