Common Strategies and Factors Affecting Off-Line Breath Sampling and Volatile Organic Compounds Analysis Using Thermal Desorption-Gas Chromatography-Mass Spectrometry (TD-GC-MS)

An analysis of exhaled breath enables specialists to noninvasively monitor biochemical processes and to determine any pathological state in the human body. Breath analysis holds the greatest potential to remold and personalize diagnostics; however, it requires a multidisciplinary approach and collab...

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Autores principales: Westphal, Kinga, Dudzik, Danuta, Waszczuk-Jankowska, Małgorzata, Graff, Beata, Narkiewicz, Krzysztof, Markuszewski, Michał Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9866406/
https://www.ncbi.nlm.nih.gov/pubmed/36676933
http://dx.doi.org/10.3390/metabo13010008
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author Westphal, Kinga
Dudzik, Danuta
Waszczuk-Jankowska, Małgorzata
Graff, Beata
Narkiewicz, Krzysztof
Markuszewski, Michał Jan
author_facet Westphal, Kinga
Dudzik, Danuta
Waszczuk-Jankowska, Małgorzata
Graff, Beata
Narkiewicz, Krzysztof
Markuszewski, Michał Jan
author_sort Westphal, Kinga
collection PubMed
description An analysis of exhaled breath enables specialists to noninvasively monitor biochemical processes and to determine any pathological state in the human body. Breath analysis holds the greatest potential to remold and personalize diagnostics; however, it requires a multidisciplinary approach and collaboration of many specialists. Despite the fact that breath is considered to be a less complex matrix than blood, it is not commonly used as a diagnostic and prognostic tool for early detection of disordered conditions due to its problematic sampling, analysis, and storage. This review is intended to determine, standardize, and marshal experimental strategies for successful, reliable, and especially, reproducible breath analysis
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spelling pubmed-98664062023-01-22 Common Strategies and Factors Affecting Off-Line Breath Sampling and Volatile Organic Compounds Analysis Using Thermal Desorption-Gas Chromatography-Mass Spectrometry (TD-GC-MS) Westphal, Kinga Dudzik, Danuta Waszczuk-Jankowska, Małgorzata Graff, Beata Narkiewicz, Krzysztof Markuszewski, Michał Jan Metabolites Review An analysis of exhaled breath enables specialists to noninvasively monitor biochemical processes and to determine any pathological state in the human body. Breath analysis holds the greatest potential to remold and personalize diagnostics; however, it requires a multidisciplinary approach and collaboration of many specialists. Despite the fact that breath is considered to be a less complex matrix than blood, it is not commonly used as a diagnostic and prognostic tool for early detection of disordered conditions due to its problematic sampling, analysis, and storage. This review is intended to determine, standardize, and marshal experimental strategies for successful, reliable, and especially, reproducible breath analysis MDPI 2022-12-21 /pmc/articles/PMC9866406/ /pubmed/36676933 http://dx.doi.org/10.3390/metabo13010008 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Westphal, Kinga
Dudzik, Danuta
Waszczuk-Jankowska, Małgorzata
Graff, Beata
Narkiewicz, Krzysztof
Markuszewski, Michał Jan
Common Strategies and Factors Affecting Off-Line Breath Sampling and Volatile Organic Compounds Analysis Using Thermal Desorption-Gas Chromatography-Mass Spectrometry (TD-GC-MS)
title Common Strategies and Factors Affecting Off-Line Breath Sampling and Volatile Organic Compounds Analysis Using Thermal Desorption-Gas Chromatography-Mass Spectrometry (TD-GC-MS)
title_full Common Strategies and Factors Affecting Off-Line Breath Sampling and Volatile Organic Compounds Analysis Using Thermal Desorption-Gas Chromatography-Mass Spectrometry (TD-GC-MS)
title_fullStr Common Strategies and Factors Affecting Off-Line Breath Sampling and Volatile Organic Compounds Analysis Using Thermal Desorption-Gas Chromatography-Mass Spectrometry (TD-GC-MS)
title_full_unstemmed Common Strategies and Factors Affecting Off-Line Breath Sampling and Volatile Organic Compounds Analysis Using Thermal Desorption-Gas Chromatography-Mass Spectrometry (TD-GC-MS)
title_short Common Strategies and Factors Affecting Off-Line Breath Sampling and Volatile Organic Compounds Analysis Using Thermal Desorption-Gas Chromatography-Mass Spectrometry (TD-GC-MS)
title_sort common strategies and factors affecting off-line breath sampling and volatile organic compounds analysis using thermal desorption-gas chromatography-mass spectrometry (td-gc-ms)
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9866406/
https://www.ncbi.nlm.nih.gov/pubmed/36676933
http://dx.doi.org/10.3390/metabo13010008
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