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Increased Expression of the Δ133p53β Isoform Enhances Brain Metastasis

The Δ133p53β isoform is increased in many primary tumors and has many tumor-promoting properties that contribute to increased proliferation, migration and inflammation. Here we investigated whether Δ133p53β contributed to some of the most aggressive tumors that had metastasized to the brain. Δ133p53...

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Detalles Bibliográficos
Autores principales: Jesus, Alexandra N. Boix De, Taha, Ahmad, Wang, David, Mehta, Paulomi M., Mehta, Sunali, Reily-Bell, Ashley, Lekamlage, Sasini Polwatta, Saraiva, Adriana Machado, Tahmeedzaman, Tahmeed, Ziad, Fouzia, Thotathil, Ziad, Gan, Peter Y. C., Royds, Janice, Braithwaite, Antony, Hung, Noelyn, Slatter, Tania L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9866425/
https://www.ncbi.nlm.nih.gov/pubmed/36674782
http://dx.doi.org/10.3390/ijms24021267