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The NLRP3 Inflammasome in Age-Related Cerebral Small Vessel Disease Manifestations: Untying the Innate Immune Response Connection

In this narrative review, we present the evidence on nucleotide-binding and oligomerization (NOD) domain-like receptor (NLR) family pyrin domain (PYD)-containing 3 (NLRP3) inflammasome activation for its putative roles in the elusive pathomechanism of aging-related cerebral small vessel disease (CSV...

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Detalles Bibliográficos
Autores principales: Che Mohd Nassir, Che Mohd Nasril, Damodaran, Thenmoly, Ismail, Nurul Iman, Hashim, Sabarisah, Jaffer, Usman, Hamid, Hafizah Abdul, Mehat, Muhammad Zulfadli, Norazit, Anwar, Mustapha, Muzaimi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9866483/
https://www.ncbi.nlm.nih.gov/pubmed/36676165
http://dx.doi.org/10.3390/life13010216

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