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Structural Analysis, Multi-Conformation Virtual Screening and Molecular Simulation to Identify Potential Inhibitors Targeting pS273R Proteases of African Swine Fever Virus

The African Swine Fever virus (ASFV) causes an infectious viral disease in pigs of all ages. The development of antiviral drugs primarily aimed at inhibition of proteases required for the proteolysis of viral polyproteins. In this study, the conformation of the pS273R protease in physiological state...

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Detalles Bibliográficos
Autores principales:	Lu, Gen, Ou, Kang, Zhang, Yihan, Zhang, Huan, Feng, Shouhua, Yang, Zuofeng, Sun, Guo, Liu, Jinling, Wei, Shu, Pan, Shude, Chen, Zeliang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9866604/ https://www.ncbi.nlm.nih.gov/pubmed/36677630 http://dx.doi.org/10.3390/molecules28020570

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