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A Novel Mast Cell Stabilizer JM25-1 Rehabilitates Impaired Gut Barrier by Targeting the Corticotropin-Releasing Hormone Receptors

Mast cell (MC) plays a central role in intestinal permeability; however, few MC-targeting drugs are currently available for protection of the intestinal barrier in clinical practice. A nonfluorinated Lidocaine analog 2-diethylamino-N-2,5-dimethylphenyl acetamide (JM25-1) displays anti-allergic effec...

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Detalles Bibliográficos
Autores principales:	Sun, Yueshan, Li, Hong, Liu, Lei, Bai, Xiaoqin, Wu, Liping, Shan, Jing, Sun, Xiaobin, Wang, Qiong, Guo, Yuanbiao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9866683/ https://www.ncbi.nlm.nih.gov/pubmed/36678544 http://dx.doi.org/10.3390/ph16010047

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