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Seroprevalence of Binding and Neutralizing Antibodies against 39 Human Adenovirus Types in Patients with Neuromuscular Disorders

High pre-existing antibodies against viral vectors reduce their functionality and may lead to adverse complications. To circumvent this problem in future gene therapy approaches, we tested the seroprevalence of a large range of human adenovirus types in patients with neuromuscular disorders (NMDs) t...

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Detalles Bibliográficos
Autores principales: Klann, Patrick Julian, Wang, Xiaoyan, Elfert, Anna, Zhang, Wenli, Köhler, Cornelia, Güttsches, Anne-Katrin, Jacobsen, Frank, Weyen, Ute, Roos, Andreas, Ehrke-Schulz, Eric, Ehrhardt, Anja, Vorgerd, Matthias, Bayer, Wibke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9866721/
https://www.ncbi.nlm.nih.gov/pubmed/36680119
http://dx.doi.org/10.3390/v15010079