Cargando…

Seroprevalence of Binding and Neutralizing Antibodies against 39 Human Adenovirus Types in Patients with Neuromuscular Disorders

High pre-existing antibodies against viral vectors reduce their functionality and may lead to adverse complications. To circumvent this problem in future gene therapy approaches, we tested the seroprevalence of a large range of human adenovirus types in patients with neuromuscular disorders (NMDs) t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Klann, Patrick Julian, Wang, Xiaoyan, Elfert, Anna, Zhang, Wenli, Köhler, Cornelia, Güttsches, Anne-Katrin, Jacobsen, Frank, Weyen, Ute, Roos, Andreas, Ehrke-Schulz, Eric, Ehrhardt, Anja, Vorgerd, Matthias, Bayer, Wibke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9866721/ https://www.ncbi.nlm.nih.gov/pubmed/36680119 http://dx.doi.org/10.3390/v15010079

Ejemplares similares

Analysis of the Prevalence of Binding and Neutralizing Antibodies against 39 Human Adenovirus Types in Student Cohorts Reveals Low-Prevalence Types and a Decline in Binding Antibody Levels during the SARS-CoV-2 Pandemic
por: Wang, Xiaoyan, et al.
Publicado: (2022)

Comparative analysis of the impact of 40 adenovirus types on dendritic cell activation and CD8(+) T cell proliferation capacity for the identification of favorable immunization vector candidates
por: Wang, Xiaoyan, et al.
Publicado: (2023)

Muscle Specific Promotors for Gene Therapy – A Comparative Study in Proliferating and Differentiated Cells
por: Dietz, Julienne, et al.
Publicado: (2023)

Spectrum-Wide Exploration of Human Adenoviruses for Breast Cancer Therapy
por: Mach, Nicolas, et al.
Publicado: (2020)

Novel Group C Oncolytic Adenoviruses Carrying a miRNA Inhibitor Demonstrate Enhanced Oncolytic Activity In Vitro and In Vivo
por: Doerner, Johannes, et al.
Publicado: (2022)

House Dust Mite Exposure Causes Increased Susceptibility of Nasal Epithelial Cells to Adenovirus Infection
por: Aydin, Malik, et al.
Publicado: (2020)

ANO5-related muscle diseases: From clinics and genetics to pathology and research strategies
por: Christiansen, Jon, et al.
Publicado: (2022)

HEHR: Homing Endonuclease-Mediated Homologous Recombination for Efficient Adenovirus Genome Engineering
por: Schröer, Katrin, et al.
Publicado: (2022)

Effect of cold atmospheric plasma (CAP) on human adenoviruses is adenovirus type-dependent
por: Bunz, Oskar, et al.
Publicado: (2018)

Influence of Heparan Sulfate Proteoglycans and Factor X on species D Human Adenovirus Uptake and Transduction
por: Schröer, Katrin, et al.
Publicado: (2022)

Quantitative muscle MRI captures early muscle degeneration in calpainopathy
por: Forsting, Johannes, et al.
Publicado: (2022)

The Adenovirus Vector Platform: Novel Insights into Rational Vector Design and Lessons Learned from the COVID-19 Vaccine
por: Sallard, Erwan, et al.
Publicado: (2023)

High Inter-Rater Reliability of Manual Segmentation and Volume-Based Tractography in Healthy and Dystrophic Human Calf Muscle
por: Forsting, Johannes, et al.
Publicado: (2021)

Diagnostic support for selected neuromuscular diseases using answer-pattern recognition and data mining techniques: a proof of concept multicenter prospective trial
por: Grigull, Lorenz, et al.
Publicado: (2016)

A High-Capacity Adenoviral Hybrid Vector System Utilizing the Hyperactive Sleeping Beauty Transposase SB100X for Enhanced Integration
por: Boehme, Philip, et al.
Publicado: (2016)

Exome Sequencing and Optical Genome Mapping in Molecularly Unsolved Cases of Duchenne Muscular Dystrophy: Identification of a Causative X-Chromosomal Inversion Disrupting the DMD Gene
por: Erbe, Leoni S., et al.
Publicado: (2023)

Identification of novel human adenovirus candidates using the coxsackievirus and adenovirus receptor for cell entry
por: Mese, Kemal, et al.
Publicado: (2020)

Microscopic and Biochemical Hallmarks of BICD2-Associated Muscle Pathology toward the Evaluation of Novel Variants
por: Unger, Andreas, et al.
Publicado: (2023)

Viral Vector-Based Delivery of CRISPR/Cas9 and Donor DNA for Homology-Directed Repair in an In Vitro Model for Canine Hemophilia B
por: Gao, Jian, et al.
Publicado: (2018)

Induction of complex immune responses and strong protection against retrovirus challenge by adenovirus-based immunization depends on the order of vaccine delivery
por: Kaulfuß, Meike, et al.
Publicado: (2017)

Comparison of polystyrene nanoparticles and UV-inactivated antigen-displaying adenovirus for vaccine delivery in mice
por: Johrden, Lena, et al.
Publicado: (2013)

Ad 2.0: a novel recombineering platform for high-throughput generation of tailored adenoviruses
por: Mück-Häusl, Martin, et al.
Publicado: (2015)

Treadmill Training with HAL Exoskeleton—A Novel Approach for Symptomatic Therapy in Patients with Limb-Girdle Muscular Dystrophy—Preliminary Study
por: Sczesny-Kaiser, Matthias, et al.
Publicado: (2017)

Low Seroprevalent Species D Adenovirus Vectors as Influenza Vaccines
por: Weaver, Eric A., et al.
Publicado: (2013)

Seroprevalence of human adenovirus type 5 neutralizing antibodies in the Philippines
por: Francisco, Abialbon G., et al.
Publicado: (2023)

Human Species D Adenoviruses Isolated from Diarrheal Feces Show Low Infection Rates in Primary Nasal Epithelial Cells
por: Aydin, Malik, et al.
Publicado: (2021)

RNAi suppressor P19 can be broadly exploited for enhanced adenovirus replication and microRNA knockdown experiments
por: Rauschhuber, Christina, et al.
Publicado: (2013)

Seroprevalence of Neutralizing Antibodies against Human Adenovirus Type-5 and Chimpanzee Adenovirus Type-68 in Cancer Patients
por: Zhao, Hua, et al.
Publicado: (2018)

Muscle imaging data in late-onset Pompe disease reveal a correlation between the pre-existing degree of lipomatous muscle alterations and the efficacy of long-term enzyme replacement therapy
por: Gruhn, Kai Michael, et al.
Publicado: (2015)

Transient Chimeric Ad5/37 Fiber Enhances NK-92 Carrier Cell-Mediated Delivery of Oncolytic Adenovirus Type 5 to Tumor Cells
por: Gao, Jian, et al.
Publicado: (2020)

Adenoviral Vectors Armed with PAPILLOMAVIRUs Oncogene Specific CRISPR/Cas9 Kill Human-Papillomavirus-Induced Cervical Cancer Cells
por: Ehrke-Schulz, Eric, et al.
Publicado: (2020)

Integration Profile and Safety of an Adenovirus Hybrid-Vector Utilizing Hyperactive Sleeping Beauty Transposase for Somatic Integration
por: Zhang, Wenli, et al.
Publicado: (2013)

Correction: Integration Profile and Safety of an Adenovirus Hybrid-Vector Utilizing Hyperactive Sleeping Beauty Transposase for Somatic Integration
por: Zhang, Wenli, et al.
Publicado: (2020)

High-Throughput Cloning and Characterization of Emerging Adenovirus Types 70, 73, 74, and 75
por: Zhang, Wenli, et al.
Publicado: (2020)

FLNC-Associated Myofibrillar Myopathy: New Clinical, Functional, and Proteomic Data
por: Kley, Rudolf Andre, et al.
Publicado: (2021)

Isoform-specific expression of the Coxsackie and adenovirus receptor (CAR) in neuromuscular junction and cardiac intercalated discs
por: Shaw, Christian A, et al.
Publicado: (2004)

Properties of Adenovirus Vectors with Increased Affinity to DSG2 and the Potential Benefits of Oncolytic Approaches and Gene Therapy
por: Bahlmann, Nora A., et al.
Publicado: (2022)

P17-22. Impact of rare adenovirus seroprevalence on HIV-1 acquisition in the Step study
por: Maxfield, LF, et al.
Publicado: (2009)

Seroprevalence of neutralizing antibodies against adenovirus type 14 and 55 in healthy adults in Southern China
por: Zheng, Xuehua, et al.
Publicado: (2017)

Comparative biological characterization of mouse adenovirus strains FL and K 87 and seroprevalence in laboratory rodents
por: Smith, A. L., et al.
Publicado: (1986)

Cannot write session to /tmp/vufind_sessions/sess_me9tqs283bugo79ecccna8eiuq