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How the Structure of Per- and Polyfluoroalkyl Substances (PFAS) Influences Their Binding Potency to the Peroxisome Proliferator-Activated and Thyroid Hormone Receptors—An In Silico Screening Study

In this study, we investigated PFAS (per- and polyfluoroalkyl substances) binding potencies to nuclear hormone receptors (NHRs): peroxisome proliferator-activated receptors (PPARs) α, β, and γ and thyroid hormone receptors (TRs) α and β. We have simulated the docking scores of 43 perfluoroalkyl comp...

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Detalles Bibliográficos
Autores principales:	Kowalska, Dominika, Sosnowska, Anita, Bulawska, Natalia, Stępnik, Maciej, Besselink, Harrie, Behnisch, Peter, Puzyn, Tomasz
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9866891/ https://www.ncbi.nlm.nih.gov/pubmed/36677537 http://dx.doi.org/10.3390/molecules28020479

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