Cargando…

Candida albicans Strains Adapted to Caspofungin Due to Aneuploidy Become Highly Tolerant under Continued Drug Pressure

Candida albicans is a prevalent fungal pathogen of humans. Understanding the development of decreased susceptibility to ECN drugs of this microbe is of substantial interest, as it is viewed as an intermediate step allowing the formation of FKS1 resistance mutations. We used six previously characteri...

Descripción completa

Detalles Bibliográficos
Autores principales:	Husain, Farha, Yadav, Anshuman, Sah, Sudisht K., Hayes, Jeffrey J., Rustchenko, Elena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9866909/ https://www.ncbi.nlm.nih.gov/pubmed/36677315 http://dx.doi.org/10.3390/microorganisms11010023

Ejemplares similares

The role of aneuploidy in the emergence of echinocandin resistance in human fungal pathogen Candida albicans
por: Sah, Sudisht Kumar, et al.
Publicado: (2021)

Genome-Wide DNA Changes Acquired by Candida albicans Caspofungin-Adapted Mutants
por: Zuber, Jeffrey, et al.
Publicado: (2023)

Cefepime and Amoxicillin Increase Metabolism and Enhance Caspofungin Tolerance of Candida albicans Biofilms
por: Cordeiro, Rossana de Aguiar, et al.
Publicado: (2019)

Management of a case of Candida albicans endogenous endophthalmitis with intravitreal caspofungin
por: Yadav, Harshali Manish, et al.
Publicado: (2017)

Tunicamycin Potentiates Antifungal Drug Tolerance via Aneuploidy in Candida albicans
por: Yang, Feng, et al.
Publicado: (2021)

Acquisition of cross-azole tolerance and aneuploidy in Candida albicans strains evolved to posaconazole
por: Kukurudz, Rebekah J, et al.
Publicado: (2022)

Antifungal activity of caspofungin in experimental infective endocarditis caused by Candida albicans
por: Victorio, Gerardo Becerra, et al.
Publicado: (2017)

Biomarkers of caspofungin resistance in Candida albicans isolates: A proteomic approach
por: De Cesare, Giuseppe Buda, et al.
Publicado: (2022)

Candida albicans Biofilm-Derived Extracellular Vesicles Are Involved in the Tolerance to Caspofungin, Biofilm Detachment, and Fungal Proteolytic Activity
por: Karkowska-Kuleta, Justyna, et al.
Publicado: (2023)

Proteomic Analysis of Caspofungin-Induced Responses in Planktonic Cells and Biofilms of Candida albicans
por: Li, Peng, et al.
Publicado: (2021)

Antifungal Susceptibility of Oral Candida Isolates from Mother-Infant Dyads to Nystatin, Fluconazole, and Caspofungin
por: Alkhars, Naemah, et al.
Publicado: (2023)

Evaluation of synergistic anticandidal and apoptotic effects of ferulic acid and caspofungin against Candida albicans
por: Canturk, Zerrin
Publicado: (2017)

Widespread Occurrence of Dosage Compensation in Candida albicans
por: Kravets, Anatoliy, et al.
Publicado: (2010)

Limitations of caspofungin in the treatment of obstructive pyonephrosis due to Candida glabrata infection
por: Schelenz, Silke, et al.
Publicado: (2006)

Aneuploidy and gene dosage regulate filamentation and host colonization by Candida albicans
por: Kakade, Pallavi, et al.
Publicado: (2023)

Transcriptional Regulation on Aneuploid Chromosomes in Diverse Candida albicans Mutants
por: Tucker, Christopher, et al.
Publicado: (2018)

Functional analysis of Candida albicans GPI-anchored proteins: Roles in cell wall integrity and caspofungin sensitivity
por: Plaine, Armêl, et al.
Publicado: (2008)

Posaconazole Exhibits In Vitro and In Vivo Synergistic Antifungal Activity with Caspofungin or FK506 against Candida albicans
por: Chen, Ying-Lien, et al.
Publicado: (2013)

Caspofungin-induced β(1,3)-glucan exposure in Candida albicans is driven by increased chitin levels
por: Wagner, Andrew S., et al.
Publicado: (2023)

Aneuploidy Underlies Tolerance and Cross-Tolerance to Drugs in Candida parapsilosis
por: Yang, Feng, et al.
Publicado: (2021)

Dual transcriptome of Streptococcus mutans and Candida albicans interplay in biofilms
por: Zeng, Yan, et al.
Publicado: (2022)

Widespread occurrence of chromosomal aneuploidy following the routine production of Candida albicans mutants
por: Arbour, Mélanie, et al.
Publicado: (2009)

Aneuploidy Mediates Rapid Adaptation to a Subinhibitory Amount of Fluconazole in Candida albicans
por: Sun, Liu-liu, et al.
Publicado: (2023)

Synergistic Activity of the Plant Defensin HsAFP1 and Caspofungin against Candida albicans Biofilms and Planktonic Cultures
por: Vriens, Kim, et al.
Publicado: (2015)

Inactivating the mannose-ethanolamine phosphotransferase Gpi7 confers caspofungin resistance in the human fungal pathogen Candida albicans
por: Zeng, Guisheng, et al.
Publicado: (2021)

The Effects of Holothurin and Caspofungin on the Vaginal Cell Inflammation Parameters of the Rattus norvegicus Strain Post Induction of Candida albicans
por: Handayani, Sri, et al.
Publicado: (2023)

Author Correction: Transcriptional Regulation on Aneuploid Chromosomes in Diverse Candida albicans Mutants
por: Tucker, Christopher, et al.
Publicado: (2019)

Candida albicans Fungaemia following Traumatic Urethral Catheterisation in a Paraplegic Patient with Diabetes Mellitus and Candiduria Treated by Caspofungin
por: Vaidyanathan, Subramanian, et al.
Publicado: (2013)

A Linear 19-Mer Plant Defensin-Derived Peptide Acts Synergistically with Caspofungin against Candida albicans Biofilms
por: Cools, Tanne L., et al.
Publicado: (2017)

Emodin Reduces the Activity of (1,3)-β-D-glucan Synthase from Candida albicans and Does Not Interact with Caspofungin
por: JANECZKO, MONIKA
Publicado: (2018)

The Tricalbin-Family Endoplasmic Reticulum-Plasma Membrane Tethering Proteins Attenuate ROS-Involved Caspofungin Sensitivity in Candida albicans
por: Yang, Li, et al.
Publicado: (2022)

Susceptibility testing of Candida albicans isolated from oropharyngeal mucosa of HIV(+) patients to fluconazole, amphotericin B and Caspofungin. killing kinetics of caspofungin and amphotericin B against fluconazole resistant and susceptible isolates
por: de Aquino Lemos, Janine, et al.
Publicado: (2009)

Transcriptional and translational landscape of Candida auris in response to caspofungin
por: Zamith-Miranda, Daniel, et al.
Publicado: (2021)

Parasexual Ploidy Reduction Drives Population Heterogeneity Through Random and Transient Aneuploidy in Candida albicans
por: Hickman, Meleah A., et al.
Publicado: (2015)

Caspofungin Inhibits Mixed Biofilms of Candida albicans and Methicillin-Resistant Staphylococcus aureus and Displays Effectiveness in Coinfected Galleria mellonella Larvae
por: Scheunemann, Gaby, et al.
Publicado: (2021)

Glucan and glycogen exist as a covalently linked macromolecular complex in the cell wall of Candida albicans and other Candida species
por: Lowman, Douglas W., et al.
Publicado: (2021)

Efficacy of humanized single large doses of caspofungin on the lethality and fungal tissue burden in a deeply neutropenic murine model against Candida albicans and Candida dubliniensis
por: Prépost, Eszter, et al.
Publicado: (2019)

Essential Role for the Phosphatidylinositol 3,5-Bisphosphate Synthesis Complex in Caspofungin Tolerance and Virulence in Candida glabrata
por: Choudhary, Deepak Kumar, et al.
Publicado: (2019)

Aneuploidy enables cross-tolerance to unrelated antifungal drugs in Candida parapsilosis
por: Sun, Liu-liu, et al.
Publicado: (2023)

Vertebral infection with Candida albicans failing caspofungin and fluconazole combination therapy but successfully treated with high dose liposomal amphotericin B and flucytosine
por: Storm, Line, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_4cq1icn8hk49e0kk28sac46ab4