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Evaluation of the Synthetic Multifunctional Peptide Hp-MAP3 Derivative of Temporin-PTa

In recent years, antimicrobial peptides isolated from amphibian toxins have gained attention as new multifunctional drugs interacting with different molecular targets. We aimed to rationally design a new peptide from temporin-PTa. Hp-MAP3 (NH(2)-LLKKVLALLKKVL-COOH), net charge (+4), hydrophobicity (...

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Detalles Bibliográficos
Autores principales: Silva, Patrícia Souza e, Guindo, Alexya Sandim, Oliveira, Pedro Henrique Cardoso, de Moraes, Luiz Filipe Ramalho Nunes, Boleti, Ana Paula de Araújo, Ferreira, Marcos Antonio, de Oliveira, Caio Fernando Ramalho, Macedo, Maria Ligia Rodrigues, Rossato, Luana, Simionatto, Simone, Migliolo, Ludovico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9866994/
https://www.ncbi.nlm.nih.gov/pubmed/36668862
http://dx.doi.org/10.3390/toxins15010042