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The Cold-Adapted, Temperature-Sensitive SARS-CoV-2 Strain TS11 Is Attenuated in Syrian Hamsters and a Candidate Attenuated Vaccine

Live attenuated vaccines (LAVs) replicate in the respiratory/oral mucosa, mimic natural infection, and can induce mucosal and systemic immune responses to the full repertoire of SARS-CoV-2 structural/nonstructural proteins. Generally, LAVs produce broader and more durable protection than current COV...

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Detalles Bibliográficos
Autores principales:	Xu, Jiayu, Liu, Mingde, Niu, Xiaoyu, Hanson, Juliette, Jung, Kwonil, Ru, Peng, Tu, Huolin, Jones, Daniel M., Vlasova, Anastasia N., Saif, Linda J., Wang, Qiuhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9867033/ https://www.ncbi.nlm.nih.gov/pubmed/36680135 http://dx.doi.org/10.3390/v15010095

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