M3 Receptor Pathway Stimulates Rapid Transcription of the CB1 Receptor Activation through Calcium Signalling and the CNR1 Gene Promoter

In this study, we have investigated a possible mechanism that enables CB(1)/M(3) receptor cross-talk, using SH-SY5Y cells as a model system. Our results show that M(3) receptor activation initiates signaling that rapidly upregulates the CNR1 gene, resulting in a greatly potentiated CB(1) receptor re...

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Detalles Bibliográficos
Autores principales: Marini, Pietro, Cowie, Philip, Ayar, Ahmet, Bewick, Guy S., Barrow, John, Pertwee, Roger G., MacKenzie, Alasdair, Tucci, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9867084/
https://www.ncbi.nlm.nih.gov/pubmed/36674826
http://dx.doi.org/10.3390/ijms24021308

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9867084/
https://www.ncbi.nlm.nih.gov/pubmed/36674826
http://dx.doi.org/10.3390/ijms24021308

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