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Gram-Positive Bacteria Cell Wall Peptidoglycan Polymers Activate Human Dendritic Cells to Produce IL-23 and IL-1β and Promote T(H)17 Cell Differentiation

Gram-positive bacterial infections are a major cause of organ failure and mortality in sepsis. Cell wall peptidoglycan (PGN) is shed during bacterial replication, and Bacillus anthracis PGN promotes a sepsis-like pathology in baboons. Herein, we determined the ability of polymeric Bacillus anthracis...

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Detalles Bibliográficos
Autores principales: Turner, Sean, Raisley, Brent, Roach, Kimberly, Bajaña, Sandra, Munroe, Melissa E., James, Judith A., Coggeshall, K. Mark, Kovats, Susan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9867153/
https://www.ncbi.nlm.nih.gov/pubmed/36677464
http://dx.doi.org/10.3390/microorganisms11010173

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