Curcumin Reduces Pathological Endoplasmic Reticulum Stress through Increasing Proteolysis of Mutant Matrilin-3

The intracellular retention of mutant cartilage matrix proteins and pathological endoplasmic reticulum (ER) stress disrupts ossification and has been identified as a shared disease mechanism in a range of skeletal dysplasias including short limbed-dwarfism, multiple epiphyseal dysplasia type 5 (EDM5...

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Detalles Bibliográficos
Autores principales: Dennis, Ella P., Watson, Robyn N., McPate, Florence, Briggs, Michael D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9867355/
https://www.ncbi.nlm.nih.gov/pubmed/36675026
http://dx.doi.org/10.3390/ijms24021496

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9867355/
https://www.ncbi.nlm.nih.gov/pubmed/36675026
http://dx.doi.org/10.3390/ijms24021496

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