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Curcumin Reduces Pathological Endoplasmic Reticulum Stress through Increasing Proteolysis of Mutant Matrilin-3

The intracellular retention of mutant cartilage matrix proteins and pathological endoplasmic reticulum (ER) stress disrupts ossification and has been identified as a shared disease mechanism in a range of skeletal dysplasias including short limbed-dwarfism, multiple epiphyseal dysplasia type 5 (EDM5...

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Detalles Bibliográficos
Autores principales:	Dennis, Ella P., Watson, Robyn N., McPate, Florence, Briggs, Michael D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9867355/ https://www.ncbi.nlm.nih.gov/pubmed/36675026 http://dx.doi.org/10.3390/ijms24021496

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