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Ageing Curtails the Diversity and Functionality of Nascent CD8(+) T Cell Responses against SARS-CoV-2

Age-related changes in the immune system are thought to underlie the vulnerability of elderly individuals to emerging viral diseases, such as coronavirus disease 2019 (COVID-19). In this study, we used a fully validated in vitro approach to determine how age impacts the generation of de novo CD8(+)...

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Detalles Bibliográficos
Autores principales: Proietto, Davide, Dallan, Beatrice, Gallerani, Eleonora, Albanese, Valentina, Llewellyn-Lacey, Sian, Price, David A., Appay, Victor, Pacifico, Salvatore, Caputo, Antonella, Nicoli, Francesco, Gavioli, Riccardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9867380/
https://www.ncbi.nlm.nih.gov/pubmed/36679999
http://dx.doi.org/10.3390/vaccines11010154