Cargando…

Small Molecule Drugs That Inhibit Phagocytosis

In our initial publication on the in vitro testing of more than 200 compounds, we demonstrated that small molecules can inhibit phagocytosis. We therefore theorized that a small molecule drug discovery-based approach to the treatment of immune cytopenias (ITP, AIHA, HTR, DHTR) is feasible. Those ear...

Descripción completa

Detalles Bibliográficos
Autores principales:	Loriamini, Melika, Lewis-Bakker, Melissa M., Frias Boligan, Kayluz, Wang, Siming, Holton, Mairead B., Kotra, Lakshmi P., Branch, Donald R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9867408/ https://www.ncbi.nlm.nih.gov/pubmed/36677815 http://dx.doi.org/10.3390/molecules28020757

Ejemplares similares

(NZW × BXSB) F1 male mice: An unusual, severe and fatal mouse model of lupus erythematosus
por: Almizraq, Ruqayyah J., et al.
Publicado: (2022)

THP-1 cells transduced with CD16A utilize Fcγ receptor I and III in the phagocytosis of IgG-sensitized human erythrocytes and platelets
por: Gil Gonzalez, Lazaro, et al.
Publicado: (2022)

Modulation of Neutrophil Function by Recombinant Human IgG1 Fc Hexamer in the Endogenous K/BxN Mouse Model of Rheumatoid Arthritis
por: Almizraq, Ruqayyah J., et al.
Publicado: (2023)

Modular adjuvant-free pan-HLA-DR-immunotargeting subunit vaccine against SARS-CoV-2 elicits broad sarbecovirus-neutralizing antibody responses
por: Kassardjian, Audrey, et al.
Publicado: (2023)

Extractions of Medical Cannabis Cultivars and the Role of Decarboxylation in Optimal Receptor Responses
por: Lewis-Bakker, Melissa M., et al.
Publicado: (2019)

Inhibition of Respiration of Candida albicans by Small Molecules Increases Phagocytosis Efficacy by Macrophages
por: Cui, Shuna, et al.
Publicado: (2020)

Opposing roles of CLK SR kinases in controlling HIV-1 gene expression and latency
por: Dahal, Subha, et al.
Publicado: (2022)

Bioactive Chemical Composition of Cannabis Extracts and Cannabinoid Receptors
por: Yang, Yi, et al.
Publicado: (2020)

Use of a Monocyte Monolayer Assay to Evaluate Fcγ Receptor-mediated Phagocytosis
por: Tong, Tik Nga, et al.
Publicado: (2017)

Infectious Diseases
por: Kotra, Lakshmi P.
Publicado: (2007)

Viral Disease
por: Kotra, Lakshmi P.
Publicado: (2007)

Chemical Profiling of Medical Cannabis Extracts
por: Lewis, Melissa M., et al.
Publicado: (2017)

Small Molecule Binding to Alzheimer Risk Factor CD33 Promotes Aβ Phagocytosis
por: Miles, Luke A., et al.
Publicado: (2019)

Siglec-7/-9 ligands shield tumor cells from NK cell attack
por: Jandus, Camilla, et al.
Publicado: (2013)

Antitumor effects of the GM3(Neu5Gc) ganglioside-specific humanized antibody 14F7hT against Cmah-transfected cancer cells
por: Dorvignit, Denise, et al.
Publicado: (2019)

Phagocytosis of Gut Bacteria by Entamoeba histolytica
por: Iyer, Lakshmi Rani, et al.
Publicado: (2019)

Cannabis sativa (Hemp) Seeds, Δ(9)-Tetrahydrocannabinol, and Potential Overdose
por: Yang, Yi, et al.
Publicado: (2017)

Inhibition of Phagocytosis by Silibinin in Mouse Macrophages
por: Sun, Kyung-Hoon, et al.
Publicado: (2023)

Unique repertoire of anti-carbohydrate antibodies in individual human serum
por: Luetscher, Ralph N. D., et al.
Publicado: (2020)

Evaluation of Radiolabeled Girentuximab In Vitro and In Vivo
por: Basaco, Tais, et al.
Publicado: (2018)

Xenogeneic Neu5Gc and self-glycan Neu5Ac epitopes are potential immune targets in MS
por: Boligan, Kayluz F., et al.
Publicado: (2020)

ABO Blood Groups Influence Macrophage-mediated Phagocytosis of Plasmodium falciparum-infected Erythrocytes
por: Wolofsky, Kayla T., et al.
Publicado: (2012)

Serum from half of patients with immune thrombocytopenia trigger macrophage phagocytosis of platelets
por: Norris, Peter A. A., et al.
Publicado: (2023)

Methamphetamine Inhibits Antigen Processing, Presentation, and Phagocytosis
por: Tallóczy, Zsolt, et al.
Publicado: (2008)

Phagocytosis
Publicado: (1892)

On Phagocytosis
Publicado: (1907)

Membrane sorting during phagocytosis: selective exclusion of major histocompatibility complex molecules but not complement receptor CR3 during conventional and coiling phagocytosis
Publicado: (1992)

Thymoquinone Effect on Monocyte-Derived Macrophages, Cell-Surface Molecule Expression, and Phagocytosis
por: Alkhattabi, Nuha A., et al.
Publicado: (2022)

A Small GTPase, RhoA, Inhibits Bacterial Infection Through Integrin Mediated Phagocytosis in Invertebrates
por: Xu, Ji-Dong, et al.
Publicado: (2018)

Correction: Methamphetamine Inhibits Antigen Processing, Presentation, and Phagocytosis
por: Tallóczy, Zsolt, et al.
Publicado: (2008)

Phagocytosis of Candida albicans Inhibits Autophagic Flux in Macrophages
por: Duan, Zhimin, et al.
Publicado: (2018)

A sequence-specific DNA binding small molecule triggers the release of immunogenic signals and phagocytosis in a model of B-cell lymphoma
por: Kang, JeenJoo S., et al.
Publicado: (2015)

Cyclobutanes in Small‐Molecule Drug Candidates
por: van der Kolk, Marnix R., et al.
Publicado: (2022)

Hypersensitivity reactions to small molecule drugs
por: Han, Jiayin, et al.
Publicado: (2022)

Small Molecule Inhibition of RISC Loading
por: Tan, Grace S., et al.
Publicado: (2011)

Inhibition of autotransporter biogenesis by small molecules
por: Steenhuis, Maurice, et al.
Publicado: (2019)

Small-Molecule Inhibition of Bacterial Biofilm
por: Ghosh, Anirban, et al.
Publicado: (2020)

Vibrio vulnificus MARTX cytotoxin causes inactivation of phagocytosis-related signaling molecules in macrophages
por: Chen, Chun-Liang, et al.
Publicado: (2017)

PD-1 expression by tumor-associated macrophages inhibits phagocytosis and tumor immunity
por: Gordon, Sydney R., et al.
Publicado: (2017)

The small molecule drug diminazene aceturate inhibits liver injury and biliary fibrosis in mice
por: Rajapaksha, Indu G., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_7ba90lneluj0vrumi4ma8nk5ju