MAPK Cascade Signaling Is Involved in α-MMC Induced Growth Inhibition of Multiple Myeloma MM.1S Cells via G2 Arrest and Mitochondrial-Pathway-Dependent Apoptosis In Vitro

Multiple myeloma is a hematological malignancy characterized by the unrestricted proliferation of plasma cells that secrete monoclonal immunoglobulins in the bone marrow. Alpha-momorcharin (α-MMC) is a type I ribosome-inactivating protein extracted from the seeds of the edible plant Momordica charan...

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Detalles Bibliográficos
Autores principales: Cai, Zi-Wei, Ye, Ting, Jiang, Pei-Wen, Liao, Yu-Jiao, Wang, Lin, Zhang, Qing-Liang, Du, Wen-Qian, Huang, Min, Yang, Ping, Li, Min-Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9867419/
https://www.ncbi.nlm.nih.gov/pubmed/36678620
http://dx.doi.org/10.3390/ph16010124

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