Cargando…

Executive function in children with disruptive mood dysregulation disorder compared to attention-deficit/hyperactivity disorder and oppositional defiant disorder, and in children with different irritability levels

Addressing current challenges in research on disruptive mood dysregulation disorder (DMDD), this study aims to compare executive function in children with DMDD, children with attention-deficit/hyperactivity disorder (ADHD), and children with oppositional defiant disorder (ODD). We also explore assoc...

Descripción completa

Detalles Bibliográficos
Autores principales: Brænden, Astrid, Coldevin, Marit, Zeiner, Pål, Stubberud, Jan, Melinder, Annika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9867548/
https://www.ncbi.nlm.nih.gov/pubmed/36680626
http://dx.doi.org/10.1007/s00787-023-02143-6
_version_ 1784876368781115392
author Brænden, Astrid
Coldevin, Marit
Zeiner, Pål
Stubberud, Jan
Melinder, Annika
author_facet Brænden, Astrid
Coldevin, Marit
Zeiner, Pål
Stubberud, Jan
Melinder, Annika
author_sort Brænden, Astrid
collection PubMed
description Addressing current challenges in research on disruptive mood dysregulation disorder (DMDD), this study aims to compare executive function in children with DMDD, children with attention-deficit/hyperactivity disorder (ADHD), and children with oppositional defiant disorder (ODD). We also explore associations between irritability, a key DMDD characteristic, and executive function in a clinical sample regardless of diagnosis. Our sample include children (6–12 years) referred to child psychiatric clinics. Measures of daily-life (parent-reported questionnaire) and performance-based (neuropsychological tasks) executive function were applied. Identifying diagnoses, clinicians administered a standardized semi-structured diagnostic interview with parents. Irritability was assessed by parent-report. First, we compared executive function in DMDD (without ADHD/ODD), ADHD (without DMDD/ODD), ODD (without DMDD/ADHD) and DMDD + ADHD (without ODD). Second, we analyzed associations between executive function and irritability using the total sample. In daily life, children with DMDD showed clinically elevated and significantly worse emotion control scores compared to children with ADHD, and clinically elevated scores on cognitive flexibility compared to norm scores. Children with DMDD had significantly less working memory problems than those with ADHD. No differences were found between DMDD and ODD. Increased irritability was positively associated with emotional dyscontrol and cognitive inflexibility. For performance-based executive function, no diagnostic differences or associations with irritability were observed. We discuss how, in daily life, children with high irritability-levels get overwhelmed by feelings without accompanying regulatory capacities. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s00787-023-02143-6.
format Online
Article
Text
id pubmed-9867548
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Springer Berlin Heidelberg
record_format MEDLINE/PubMed
spelling pubmed-98675482023-01-23 Executive function in children with disruptive mood dysregulation disorder compared to attention-deficit/hyperactivity disorder and oppositional defiant disorder, and in children with different irritability levels Brænden, Astrid Coldevin, Marit Zeiner, Pål Stubberud, Jan Melinder, Annika Eur Child Adolesc Psychiatry Original Contribution Addressing current challenges in research on disruptive mood dysregulation disorder (DMDD), this study aims to compare executive function in children with DMDD, children with attention-deficit/hyperactivity disorder (ADHD), and children with oppositional defiant disorder (ODD). We also explore associations between irritability, a key DMDD characteristic, and executive function in a clinical sample regardless of diagnosis. Our sample include children (6–12 years) referred to child psychiatric clinics. Measures of daily-life (parent-reported questionnaire) and performance-based (neuropsychological tasks) executive function were applied. Identifying diagnoses, clinicians administered a standardized semi-structured diagnostic interview with parents. Irritability was assessed by parent-report. First, we compared executive function in DMDD (without ADHD/ODD), ADHD (without DMDD/ODD), ODD (without DMDD/ADHD) and DMDD + ADHD (without ODD). Second, we analyzed associations between executive function and irritability using the total sample. In daily life, children with DMDD showed clinically elevated and significantly worse emotion control scores compared to children with ADHD, and clinically elevated scores on cognitive flexibility compared to norm scores. Children with DMDD had significantly less working memory problems than those with ADHD. No differences were found between DMDD and ODD. Increased irritability was positively associated with emotional dyscontrol and cognitive inflexibility. For performance-based executive function, no diagnostic differences or associations with irritability were observed. We discuss how, in daily life, children with high irritability-levels get overwhelmed by feelings without accompanying regulatory capacities. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s00787-023-02143-6. Springer Berlin Heidelberg 2023-01-21 /pmc/articles/PMC9867548/ /pubmed/36680626 http://dx.doi.org/10.1007/s00787-023-02143-6 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Original Contribution
Brænden, Astrid
Coldevin, Marit
Zeiner, Pål
Stubberud, Jan
Melinder, Annika
Executive function in children with disruptive mood dysregulation disorder compared to attention-deficit/hyperactivity disorder and oppositional defiant disorder, and in children with different irritability levels
title Executive function in children with disruptive mood dysregulation disorder compared to attention-deficit/hyperactivity disorder and oppositional defiant disorder, and in children with different irritability levels
title_full Executive function in children with disruptive mood dysregulation disorder compared to attention-deficit/hyperactivity disorder and oppositional defiant disorder, and in children with different irritability levels
title_fullStr Executive function in children with disruptive mood dysregulation disorder compared to attention-deficit/hyperactivity disorder and oppositional defiant disorder, and in children with different irritability levels
title_full_unstemmed Executive function in children with disruptive mood dysregulation disorder compared to attention-deficit/hyperactivity disorder and oppositional defiant disorder, and in children with different irritability levels
title_short Executive function in children with disruptive mood dysregulation disorder compared to attention-deficit/hyperactivity disorder and oppositional defiant disorder, and in children with different irritability levels
title_sort executive function in children with disruptive mood dysregulation disorder compared to attention-deficit/hyperactivity disorder and oppositional defiant disorder, and in children with different irritability levels
topic Original Contribution
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9867548/
https://www.ncbi.nlm.nih.gov/pubmed/36680626
http://dx.doi.org/10.1007/s00787-023-02143-6
work_keys_str_mv AT brændenastrid executivefunctioninchildrenwithdisruptivemooddysregulationdisordercomparedtoattentiondeficithyperactivitydisorderandoppositionaldefiantdisorderandinchildrenwithdifferentirritabilitylevels
AT coldevinmarit executivefunctioninchildrenwithdisruptivemooddysregulationdisordercomparedtoattentiondeficithyperactivitydisorderandoppositionaldefiantdisorderandinchildrenwithdifferentirritabilitylevels
AT zeinerpal executivefunctioninchildrenwithdisruptivemooddysregulationdisordercomparedtoattentiondeficithyperactivitydisorderandoppositionaldefiantdisorderandinchildrenwithdifferentirritabilitylevels
AT stubberudjan executivefunctioninchildrenwithdisruptivemooddysregulationdisordercomparedtoattentiondeficithyperactivitydisorderandoppositionaldefiantdisorderandinchildrenwithdifferentirritabilitylevels
AT melinderannika executivefunctioninchildrenwithdisruptivemooddysregulationdisordercomparedtoattentiondeficithyperactivitydisorderandoppositionaldefiantdisorderandinchildrenwithdifferentirritabilitylevels