Neuroprotective effect of astragalin via activating PI3K/Akt-mTOR-mediated autophagy on APP/PS1 mice

As a small molecule flavonoid, astragalin (AST) has anti-inflammatory, anti-cancer, and anti-oxidation effects. However, the impact and molecular mechanism of AST in Alzheimer’s disease (AD) are still not clear. This study aims to investigate the neuroprotective effect and mechanism of AST on APP/PS...

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Detalles Bibliográficos
Autores principales: Yang, Cui-Zhu, Wang, Shu-Han, Zhang, Run-Heng, Lin, Jia-Hong, Tian, Ying-Hong, Yang, Ya-Qi, Liu, Jing, Ma, Yu-Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9867706/
https://www.ncbi.nlm.nih.gov/pubmed/36681681
http://dx.doi.org/10.1038/s41420-023-01324-1

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