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Glucocorticoids coordinate the bladder peripheral clock and diurnal micturition pattern in mice

Peripheral clocks function to regulate each organ and are synchronized though various molecular and behavioral signals. However, signals that entrain the bladder clock remain elusive. Here, we show that glucocorticoids are a key cue for the bladder clock in vitro and in vivo. A pBmal1-dLuc human uro...

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Detalles Bibliográficos
Autores principales: Chihara, Ichiro, Negoro, Hiromitsu, Kono, Jin, Nagumo, Yoshiyuki, Tsuchiya, Haruki, Kojo, Kosuke, Shiga, Masanobu, Tanaka, Ken, Kandori, Shuya, Mathis, Bryan J., Nishiyama, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9867708/
https://www.ncbi.nlm.nih.gov/pubmed/36681730
http://dx.doi.org/10.1038/s42003-023-04464-3