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Glucocorticoids coordinate the bladder peripheral clock and diurnal micturition pattern in mice
Peripheral clocks function to regulate each organ and are synchronized though various molecular and behavioral signals. However, signals that entrain the bladder clock remain elusive. Here, we show that glucocorticoids are a key cue for the bladder clock in vitro and in vivo. A pBmal1-dLuc human uro...
Autores principales: | Chihara, Ichiro, Negoro, Hiromitsu, Kono, Jin, Nagumo, Yoshiyuki, Tsuchiya, Haruki, Kojo, Kosuke, Shiga, Masanobu, Tanaka, Ken, Kandori, Shuya, Mathis, Bryan J., Nishiyama, Hiroyuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9867708/ https://www.ncbi.nlm.nih.gov/pubmed/36681730 http://dx.doi.org/10.1038/s42003-023-04464-3 |
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