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Excitatory/inhibitory imbalance in autism: the role of glutamate and GABA gene-sets in symptoms and cortical brain structure

The excitatory/inhibitory (E/I) imbalance hypothesis posits that imbalance between excitatory (glutamatergic) and inhibitory (GABAergic) mechanisms underlies the behavioral characteristics of autism. However, how E/I imbalance arises and how it may differ across autism symptomatology and brain regio...

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Detalles Bibliográficos
Autores principales:	Hollestein, Viola, Poelmans, Geert, Forde, Natalie J., Beckmann, Christian F., Ecker, Christine, Mann, Caroline, Schäfer, Tim, Moessnang, Carolin, Baumeister, Sarah, Banaschewski, Tobias, Bourgeron, Thomas, Loth, Eva, Dell’Acqua, Flavio, Murphy, Declan G. M., Puts, Nicolaas A., Tillmann, Julian, Charman, Tony, Jones, Emily J. H., Mason, Luke, Ambrosino, Sara, Holt, Rosemary, Bölte, Sven, Buitelaar, Jan K., Naaijen, Jilly
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9867712/ https://www.ncbi.nlm.nih.gov/pubmed/36681677 http://dx.doi.org/10.1038/s41398-023-02317-5

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