Epithelial disruption drives mesendoderm differentiation in human pluripotent stem cells by enabling TGF-β protein sensing

The processes of primitive streak formation and fate specification in the mammalian epiblast rely on complex interactions between morphogens and tissue organization. Little is known about how these instructive cues functionally interact to regulate gastrulation. We interrogated the interplay between...

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Detalles Bibliográficos
Autores principales: Legier, Thomas, Rattier, Diane, Llewellyn, Jack, Vannier, Thomas, Sorre, Benoit, Maina, Flavio, Dono, Rosanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9867713/
https://www.ncbi.nlm.nih.gov/pubmed/36681697
http://dx.doi.org/10.1038/s41467-023-35965-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9867713/
https://www.ncbi.nlm.nih.gov/pubmed/36681697
http://dx.doi.org/10.1038/s41467-023-35965-8

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