Cargando…
Nuclear receptor modulators inhibit osteosarcoma cell proliferation and tumour growth by regulating the mTOR signaling pathway
Osteosarcoma is the most common primary malignant bone tumour in children and adolescents. Chemoresistance leads to poor responses to conventional therapy in patients with osteosarcoma. The discovery of novel effective therapeutic targets and drugs is still the main focus of osteosarcoma research. N...
Autores principales: | Yuan, Baoshi, Shi, Kexin, Zha, Juanmin, Cai, Yujia, Gu, Yue, Huang, Kai, Yue, Wenchang, Zhai, Qiaocheng, Ding, Ning, Ren, Wenyan, He, Weiqi, Xu, Ying, Wang, Tao |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9867777/ https://www.ncbi.nlm.nih.gov/pubmed/36681687 http://dx.doi.org/10.1038/s41419-022-05545-7 |
Ejemplares similares
-
mTOR: An attractive therapeutic target for osteosarcoma?
por: Ding, Liu, et al.
Publicado: (2016) -
mTOR pathway activation in multiple myeloma cell lines and primary tumour cells: pomalidomide enhances cytoplasmic-nuclear shuttling of mTOR protein
por: Guglielmelli, Tommasina, et al.
Publicado: (2015) -
Peroxiredoxin-1 promotes cell proliferation and metastasis through enhancing Akt/mTOR in human osteosarcoma cells
por: Cai, An-Lie, et al.
Publicado: (2017) -
Chitosan oligosaccharide suppresses osteosarcoma malignancy by inhibiting CEMIP via the PI3K/AKT/mTOR pathway
por: Sim, IlJin, et al.
Publicado: (2023) -
mTOR-Dependent Cell Proliferation in the Brain
por: Ryskalin, Larisa, et al.
Publicado: (2017)