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AMPK attenuates SHH subgroup medulloblastoma growth and metastasis by inhibiting NF-κB activation
BACKGROUND: Medulloblastoma (MB) is one of the most common malignant pediatric brain tumors. Metastasis and relapse are the leading causes of death in MB patients. The initiation of the SHH subgroup of MB (SHH-MB) is due to the aberrant activation of Sonic Hedgehog (Shh) signaling. However, the mech...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9867863/ https://www.ncbi.nlm.nih.gov/pubmed/36683064 http://dx.doi.org/10.1186/s13578-023-00963-2 |