AMPK attenuates SHH subgroup medulloblastoma growth and metastasis by inhibiting NF-κB activation

BACKGROUND: Medulloblastoma (MB) is one of the most common malignant pediatric brain tumors. Metastasis and relapse are the leading causes of death in MB patients. The initiation of the SHH subgroup of MB (SHH-MB) is due to the aberrant activation of Sonic Hedgehog (Shh) signaling. However, the mech...

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Detalles Bibliográficos
Autores principales: Cai, Jing, Wang, Yue, Wang, Xinfa, Ai, Zihe, Li, Tianyuan, Pu, Xiaohong, Yang, Xin, Yao, Yixing, He, Junping, Cheng, Steven Y., Yu, Tingting, Liu, Chen, Yue, Shen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9867863/
https://www.ncbi.nlm.nih.gov/pubmed/36683064
http://dx.doi.org/10.1186/s13578-023-00963-2

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