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An optimized Western blot assay provides a comprehensive assessment of the physiological endoproteolytic processing of the prion protein

The prion protein (PrP(C)) is subjected to several conserved endoproteolytic events producing bioactive fragments that are of increasing interest for their physiological functions and their implication in the pathogenesis of prion diseases and other neurodegenerative diseases. However, systematic an...

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Detalles Bibliográficos
Autores principales:	Vanni, Ilaria, Iacobone, Floriana, D’Agostino, Claudia, Giovannelli, Matteo, Pirisinu, Laura, Altmeppen, Hermann Clemens, Castilla, Joaquin, Torres, Juan Maria, Agrimi, Umberto, Nonno, Romolo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9867980/ https://www.ncbi.nlm.nih.gov/pubmed/36565989 http://dx.doi.org/10.1016/j.jbc.2022.102823

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