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Mitochondria-localized lncRNA HITT inhibits fusion by attenuating formation of mitofusin-2 homotypic or heterotypic complexes

Long noncoding RNAs (lncRNAs) are emerging as essential players in multiple biological processes. Mitochondrial dynamics, comprising the continuous cycle of fission and fusion, are required for healthy mitochondria that function properly. Despite long-term recognition of its significance in cell-fat...

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Detalles Bibliográficos
Autores principales: Wang, Xingwen, Zhang, Yi, Lin, Qingyu, Zhao, Kunming, Zhu, Dantong, Hu, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9867983/
https://www.ncbi.nlm.nih.gov/pubmed/36567017
http://dx.doi.org/10.1016/j.jbc.2022.102825