Cargando…

A Primary Lung and Breast Cancer Patient with Germline EGFR R776H Mutation: A Case Report and Literature Review

For advanced non-small cell lung cancer (NSCLC) patients with common epidermal growth factor receptor (EGFR) mutations (exon 19 deletions or the exon 21 L858R mutation), tyrosine kinase inhibitors (TKIs) are the standard therapies. However, EGFR germline mutations are extremely rare in lung cancer,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Dan, Liu, Xin, Cui, SaiQiong, Yang, DaFu, Zhu, Yue, Pan, Evenki, Yang, Peng, Dai, ZhaoXia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2023
Materias:	Case Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9868143/ https://www.ncbi.nlm.nih.gov/pubmed/36698436 http://dx.doi.org/10.2147/OTT.S391766

Ejemplares similares

NGS-Based ctDNA Profiling After the Resistance of Second-Line Osimertinib for Patient with EGFR-Mutated Pulmonary Adenocarcinoma
por: Li, Dan, et al.
Publicado: (2021)

Lung adenocarcinoma patients with novel ALK fusion variants and their clinical responses to ALK inhibitors
por: Yang, Dafu, et al.
Publicado: (2021)

The broad spectrum of tyrosine kinase inhibitors. Treatment of a rare EGFR R776H mutation with Osimertinib: Case report
por: Cui, Joyce, et al.
Publicado: (2023)

Case Report: Lung adenocarcinoma associated with germline ERCC2 frameshift mutation
por: Liu, Lili, et al.
Publicado: (2023)

Efficacy of afatinib in a patient with rare EGFR (G724S/R776H) mutations and amplification in lung adenocarcinoma: A case report
por: He, Shu-Yan, et al.
Publicado: (2021)

776 Quality Improvement in Prehospital Burn Care
por: Phillips, Frank, et al.
Publicado: (2022)

Germline EGFR mutations in lung cancer (Review)
por: Liu, Minghui, et al.
Publicado: (2023)

776 Importance of Adequate Nutrition Support in Severely Burned Patients
por: Stone, Amanda
Publicado: (2023)

776. Clinical Practice Gap Analysis of Physicians’ Understanding of Cytomegalovirus
por: Larkin, Amy, et al.
Publicado: (2023)

Tumor Heterogeneity and Drug Resistance Mutations Using ctDNA in Metastatic EGFR Mutation-Positive Lung Adenocarcinoma: A Case Report
por: Sun, Jinghua, et al.
Publicado: (2022)

Germline mutations and developmental mosaicism underlying EGFR-mutant lung cancer
por: Burr, Risa, et al.
Publicado: (2023)

Modulation of ATXN1 S776 phosphorylation reveals the importance of allele-specific targeting in SCA1
por: Nitschke, Larissa, et al.
Publicado: (2021)

The importance of serine 776 in Ataxin-1 partner selection: A FRET Analysis
por: Menon, Rajesh P., et al.
Publicado: (2012)

Favorable Response to Olaparib in a Patient with Cancer of Unknown Primary Carrying a Germline BRCA1 R71K Mutation
por: Jia, Xiaomeng, et al.
Publicado: (2021)

HER2 G776S mutation promotes oncogenic potential in colorectal cancer cells when accompanied by loss of APC function
por: Mitani, Yosuke, et al.
Publicado: (2022)

Prevalence of Pathological Germline Mutations of hMLH1 and hMSH2 Genes in Colorectal Cancer
por: Li, Dandan, et al.
Publicado: (2013)

Severe ineffective erythropoiesis discriminates prognosis in myelodysplastic syndromes: analysis based on 776 patients from a single centre
por: Huang, Huijun, et al.
Publicado: (2020)

Novel EGFR V834L Germline Mutation Associated With Familial Lung Adenocarcinoma
por: van der Leest, Cor, et al.
Publicado: (2018)

Case report: Neuroendocrine breast carcinoma with a germline EGFR T790M mutation
por: Sagan, Olivia A., et al.
Publicado: (2023)

Phosphorylation of S776 and 14-3-3 Binding Modulate Ataxin-1 Interaction with Splicing Factors
por: de Chiara, Cesira, et al.
Publicado: (2009)

776 Acinetobacter baumannii ventilator acquired pneumonia in a high density unit of North India
por: Sharma, Navneet, et al.
Publicado: (2014)

Efficient Everolimus Treatment for Metastatic Castration Resistant Prostate Cancer with AKT1 Mutation: A Case Report
por: Yu, Zhe, et al.
Publicado: (2021)

Potential genetic modifiers for somatic EGFR mutation in lung cancer: a meta-analysis and literature review
por: Cheng, Yue I., et al.
Publicado: (2019)

Exome sequencing reveals germline gain-of-function EGFR mutation in an adult with Lhermitte–Duclos disease
por: Colby, Samantha, et al.
Publicado: (2016)

Predisposition to Lung Adenocarcinoma in a Family Harboring the Germline EGFR V843I Mutation
por: Ohtsuka, Kouki, et al.
Publicado: (2019)

Genomic Evolution in a Patient With Lung Adenocarcinoma With a Germline EGFR T790M Mutation
por: Mäkinen, Netta, et al.
Publicado: (2021)

776. Tuberculosis Screening Among People Living With HIV in Arkansas: A Ryan White Program Evaluation
por: Gu, Mofan, et al.
Publicado: (2018)

Infectious disease specialist consultations in a Japanese cancer center: a retrospective review of 776 cases
por: Itoh, Naoya, et al.
Publicado: (2020)

Scattering properties and femtosecond laser ablation thresholds of human and canine vocal folds at 776-nm wavelength
por: Andrus, Liam, et al.
Publicado: (2019)

776. Effect of the SEP-1 Sepsis Bundle on Mortality in Hospital-Onset v. Community-Onset Sepsis
por: Baghdadi, Jonathan, et al.
Publicado: (2019)

Impact of sex differences in co‐morbidities and medication adherence on outcome in 25 776 heart failure patients
por: Gürgöze, Muhammed T., et al.
Publicado: (2020)

A refractory liver metastatic solid pseudopapillary neoplasm pancreas harbored CTNNB1 mutation showed good response to celecoxib: A case report
por: Shang, Yu, et al.
Publicado: (2022)

Association between EGFR mutation and expression of BRCA1 and RAP80 in non-small cell lung cancer
por: Sun, Xia, et al.
Publicado: (2018)

Transcobalamin C776G Genotype Modifies the Association between Vitamin B12 and Homocysteine in Older Hispanics
por: Garrod, Marjorie G., et al.
Publicado: (2010)

A measurement of the differential cross section for elastic pion-helium scattering at 7.76 GeV/c
por: Ekelöf, T J C, et al.
Publicado: (1971)

Association of transcobalamin c. 776C>G with overall survival in patients with primary central nervous system lymphoma
por: Linnebank, M, et al.
Publicado: (2012)

Draft Genome Sequence of the Butyric Acid Producer Clostridium tyrobutyricum Strain CIP I-776 (IFP923)
por: Wasels, François, et al.
Publicado: (2016)

14-3-3 Binding to Ataxin-1(ATXN1) Regulates Its Dephosphorylation at Ser-776 and Transport to the Nucleus
por: Lai, Shaojuan, et al.
Publicado: (2011)

Diagnosis of anorectal tuberculosis by polymerase chain reaction, GeneXpert and histopathology in 1336 samples in 776 anal fistula patients
por: Garg, Pankaj, et al.
Publicado: (2021)

776. The prevalence of HIV among hospitalized persons with acute febrile illness in rural Uganda, August 2019-June 2020
por: Blair, Paul W, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_2u2qt1dvfkr3ak9m2ualbo5b6b