Cargando…

Partially replacing cyclophosphamide with bendamustine in combination with cyclosporine A improves survival and reduces xenogeneic graft-versus-host-disease

INTRODUCTION: The use of allogeneic hematopoietic cell transplantation (allo-HCT) for treating hematological disorders is increasing, but the development of graft-versus-host disease (GvHD) remains a major cause of morbidity and mortality. The use of post-transplant cyclophosphamide (CY) has signifi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gilman, Kristy E., Cracchiolo, Megan J., Matiatos, Andrew P., Davini, Dan W., Simpson, Richard J., Katsanis, Emmanuel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9868157/ https://www.ncbi.nlm.nih.gov/pubmed/36700195 http://dx.doi.org/10.3389/fimmu.2022.1045710

Ejemplares similares

Multiagent Intratumoral Immunotherapy Can Be Effective in A20 Lymphoma Clearance and Generation of Systemic T Cell Immunity
por: Gilman, Kristy E., et al.
Publicado: (2023)

Progressive substitution of posttransplant cyclophosphamide with bendamustine: A phase I study in haploidentical bone marrow transplantation
por: Katsanis, Emmanuel, et al.
Publicado: (2020)

Immunomodulatory Effects of Bendamustine in Hematopoietic Cell Transplantation
por: Stokes, Jessica, et al.
Publicado: (2021)

Bendamustine with total body irradiation conditioning yields tolerant T-cells while preserving T-cell-dependent graft-versus-leukemia
por: Stokes, Jessica, et al.
Publicado: (2020)

Bendamustine Conditioning Skews Murine Host DCs Toward Pre-cDC1s and Reduces GvHD Independently of Batf3
por: Molina, Megan S., et al.
Publicado: (2020)

Post-transplant cyclophosphamide prevents xenogeneic graft-versus-host disease while depleting proliferating regulatory T cells
por: Ritacco, Caroline, et al.
Publicado: (2023)

Regulatory Dendritic Cells Induced by Bendamustine Are Associated With Enhanced Flt3 Expression and Alloreactive T-Cell Death
por: Molina, Megan S., et al.
Publicado: (2021)

Sirolimus versus cyclosporine in haploidentical stem cell transplantation with posttransplant cyclophosphamide and mycophenolate mofetil as graft‐versus‐host disease prophylaxis
por: Hernani, Rafael, et al.
Publicado: (2021)

Human lymphocytes mobilized with exercise have an anti-tumor transcriptomic profile and exert enhanced graft-versus-leukemia effects in xenogeneic mice
por: Batatinha, Helena, et al.
Publicado: (2023)

CD4(+)CD8(+) T-Lymphocytes in Xenogeneic and Human Graft-versus-Host Disease
por: Alhaj Hussen, Kutaiba, et al.
Publicado: (2020)

Intravesical Administration of Xenogeneic Porcine Urothelial Cells Attenuates Cyclophosphamide-Induced Cystitis in Mice
por: Huang, Chi-Ping, et al.
Publicado: (2019)

Bendamustine vs. fludarabine/cyclophosphamide lymphodepletion prior to BCMA CAR-T cell therapy in multiple myeloma
por: Sidana, Surbhi, et al.
Publicado: (2023)

Commentary: Post-Transplantation Cyclophosphamide Uniquely Restrains Alloreactive CD4+ T-Cell Proliferation and Differentiation After Murine MHC-Haploidentical Hematopoietic Cell Transplantation
por: Stokes, Jessica, et al.
Publicado: (2022)

In Vivo Depletion of Lymphotoxin-Alpha Expressing Lymphocytes Inhibits Xenogeneic Graft-versus-Host-Disease
por: Chiang, Eugene Y., et al.
Publicado: (2012)

Xenogeneic Graft-Versus-Host Disease in Humanized NSG and NSG-HLA-A2/HHD Mice
por: Ehx, Grégory, et al.
Publicado: (2018)

Human LAP(+)GARP(+)FOXP3(+) regulatory T cells attenuate xenogeneic graft versus host disease
por: Wang, Huihui, et al.
Publicado: (2019)

THE INDUCTION OF GRAFT VERSUS HOST DISEASE IN MICE TREATED WITH CYCLOPHOSPHAMIDE
por: Owens, Albert H., et al.
Publicado: (1968)

Stable multilineage xenogeneic replacement of definitive hematopoiesis in adult zebrafish
por: Hess, Isabell, et al.
Publicado: (2016)

Low cyclosporine concentrations in children and time to acute graft versus host disease
por: Chung, Eun Kyung, et al.
Publicado: (2020)

Xenogeneic skin graft rejection is especially dependent on CD4+ T cells
Publicado: (1989)

Decellularized xenogenic bone graft for repair of segmental bone defect in rabbits
por: Tamilmahan, P., et al.
Publicado: (2022)

Effect of cyclosporin A on the anti-leukaemia action associated with graft-versus-host disease.
por: Denham, S., et al.
Publicado: (1983)

Requirements for the induction and adoptive transfer of cyclosporine- induced syngeneic graft-versus-host disease
Publicado: (1989)

Human amnion-derived mesenchymal stem cells attenuate xenogeneic graft-versus-host disease by preventing T cell activation and proliferation
por: Tago, Yoshiyuki, et al.
Publicado: (2021)

Tomographic late evaluation of xenogeneic bone grafts in sockets of impacted third molars
por: FERREIRA JÚNIOR, Osny, et al.
Publicado: (2018)

Oral mucositis after tacrolimus/sirolimus or cyclosporine/methotrexate as graft‐versus‐host disease prophylaxis
por: Garming Legert, Karin, et al.
Publicado: (2020)

Cyclophosphamide for salvage therapy of chronic graft-versus-host disease: a retrospective analysis
por: Fante, Matthias A., et al.
Publicado: (2020)

Mechanisms of Graft-versus-Host Disease Prevention by Post-transplantation Cyclophosphamide: An Evolving Understanding
por: Nunes, Natalia S., et al.
Publicado: (2019)

Could Salivary Cyclosporine Dosage Replace the Whole Blood Cyclosporine Measurements in Renal Transplant Patients?
por: Aboujaoude, Samia, et al.
Publicado: (2017)

Xenogenic Adenoviral Vectors
por: Mittal, Suresh K., et al.
Publicado: (2016)

Xenogenic Adenoviral Vectors
por: Both, Gerald W.
Publicado: (2002)

Daratumumab Prevents Experimental Xenogeneic Graft-Versus-Host Disease by Skewing Proportions of T Cell Functional Subsets and Inhibiting T Cell Activation and Migration
por: Gao, Yang, et al.
Publicado: (2021)

Immunological reactions induced by bendamustine
por: Sanchez-Gonzalez, Maria-Jose, et al.
Publicado: (2014)

Successful Xenogeneic Transplantation in Embryos: Induction of Tolerance by Extrathymic Chick Tissue Grafted into Quail
por: Martin, Claude, et al.
Publicado: (1991)

Anti-Inflammatory Thalidomide Improves Islet Grafts Survival and Functions in a Xenogenic Environment
por: Chen, Chunguang, et al.
Publicado: (2009)

Topical Delivery of Immunosuppression to Prolong Xenogeneic and Allogeneic Split-Thickness Skin Graft Survival
por: Mastroianni, Melissa, et al.
Publicado: (2018)

Repairing whole facial nerve defects with xenogeneic acellular nerve grafts in rhesus monkeys
por: Zhu, Guo-Chen, et al.
Publicado: (2021)

Xenogeneic Graft-versus-Host-Disease in NOD-scid IL-2Rγ(null) Mice Display a T-Effector Memory Phenotype
por: Ali, Niwa, et al.
Publicado: (2012)

GM-CSF Promotes the Expansion and Differentiation of Cord Blood Myeloid-Derived Suppressor Cells, Which Attenuate Xenogeneic Graft-vs.-Host Disease
por: Park, Mi-Young, et al.
Publicado: (2019)

Randomized phase 2 study of otlertuzumab and bendamustine versus bendamustine in patients with relapsed chronic lymphocytic leukaemia
por: Robak, Tadeusz, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_q3othljltkhljiu0uk58v7h95e